Results 241 to 250 of about 1,420,670 (291)
Contractility of isolated single submucosal gland from trachea
Journal of Applied Physiology, 1986 We isolated single submucosal glands from canine and feline trachea. Examination by light and electron microscope showed that these isolated glands consist mainly of glandular tissue, and no smooth muscle. Cell components in the glandular tissue were ultrastructurally normal, and myoepithelial cells surrounded acini and secretory tubules.
S, Shimura +3 more
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Effect of dantrolene sodium in isolated guinea-pig trachea
European Journal of Pharmacology, 1990The effect of dantrolene sodium (3 microM-0.3 mM) on the spontaneous tone and responses to various contractile agonists was studied in isolated guinea-pig trachea. Dantrolene produced a concentration-related inhibition of the spontaneous tracheal tone, reaching a value of 94.8 +/- 4.8% of the relaxation induced by caffeine 10 mM.
Esteban Morcillo, Miguel Perpiñá
exaly +3 more sources
Inhibition of antigen-induced tone in isolated trachea
European Journal of Pharmacology, 1975The relaxing effect of the beta-adrenoceptor stimulating agent terbutaline was studied on the spirally cut trachea from actively ovalbumin-sensitized guinea pigs. Terbutaline counteracted the antigen-induced muscular tone more effectively when added 5 min before the addition of the antigen than when added at the peak effect. The reason for the improved
exaly +3 more sources
Mechanical properties of the isolated equine trachea
Research in Veterinary Science, 1991In order to study the in vitro mechanical properties of the equine trachea submitted to the compressive pressures observed in vivo, the pressure-volume relationship was determined in intra- and extra-thoracic tracheal segments taken post mortem from 29 healthy horses (one to 15 years old; 352 to 651 kg). At the same time, the cross-sectional lumen area
Art, Tatiana, Lekeux, Pierre
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The effect of xylazine on the isolated sheep trachea
Journal of Veterinary Pharmacology and Therapeutics, 1995The effect of xylazine on the isolated sheep trachea and its possible interactions with the α2‐adrenergic antagonist, atipamezole, and the anticholinergic agent, atropine, was studied. The mechanical responses of the tracheal preparations were recorded after exposing each one to cumulatively increasing concentrations of xylazine alone or in the ...
L, Papazoglou +2 more
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DA1 Receptors Modulation in Rat Isolated Trachea
American Journal of Therapeutics, 2010We have previously demonstrated that low dose of inhaled dopamine (0.5-2 microg kg(-1) min(-1)) induces broncodilatacion in patients with acute asthma attack, suggesting that this dopamine effect is mediated by dopaminergic rather than by adrenergic receptors. To understand better these dopamine effect, rat tracheal smooth muscle was used as a model to
Gloria A, Cabezas, Manuel, Velasco
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Transepithelial prostacyclin gradient in isolated canine trachea
Journal of Applied Physiology, 1989Cyclooxygenase products of arachidonic acid, potential modulators of airway smooth muscle, have recently been described in bronchoalveolar lavage from canine lungs. To evaluate the possibility that airway epithelium represents a barrier to movement of prostacyclin (PGI2), an important bronchodilator synthesized by isolated airway, we measured the ...
D H, Eidelman +3 more
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Pharmacology and mode of action of bradykinin on mouse-isolated trachea
Naunyn-Schmiedeberg's Archives of Pharmacology, 1997In the present study, the effect of bradykinin on basal and precontracted mouse-isolated trachea was investigated. In basal conditions mouse-isolated tracheal rings do not respond to bradykinin. However, when the tracheal rings were precontracted with carbachol (10(-7) M) a relaxation with bradykinin (3 x 10(-9)-3 x 10(-7)) was found.
D, van Heuven-Nolsen +5 more
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Inhibitory Effect of Amitriptyline on Contraction of the Rat Isolated Trachea
Pharmacology, 2008The effects of amitriptyline, a tricyclic antidepressant, on contractile responses to exogenously applied acetylcholine, endothelin 1 and high K+ were examined in the rat isolated trachea. Amitriptyline (0.3–30 µmol/l) produced a shift to the right of the logarithmic acetylcholine concentration-contraction curve without affecting the maximum ...
Y, Huang, C W, Lau
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