Results 91 to 100 of about 2,248,440 (315)

Synergy I: Marginalisation, Discrimination, Isolation and Existence in Literature

open access: yes, 2021
Studies on the distinguished works of English and American literature of various genres like poetry, plays and fiction are included in this book focusing on and around the central themes of "Marginalisation, Discrimination, Isolation, and Existence." The
Töngür, A. Nejat, Çevik, Yildiray
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Rock mechanics activities at the Waste Isolation Pilot Plant [PDF]

open access: yes, 1996
The application of rock mechanics at nuclear waste repositories is a true multidisciplinary effort. A description and historical summary of the Waste Isolation Pilot Plant (WIPP) is presented.
Saeb, S., Francke, C.
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Multicenter Assessment of Animal-free Collagenase AF-1 for Human Islet Isolation

open access: yesCell Transplantation, 2017
Animal-free (AF) SERVA Collagenase AF-1 and Neutral Protease (NP) AF GMP Grade have recently become available for human islet isolation. This report describes the initial experiences of 3 different islet transplant centers.
Daniel Brandhorst   +10 more
doaj   +1 more source

Proceedings of the workshop 'Isolation of operators as a consequence of automation'

open access: yes, 1987
'Isolation' beschreibt den physikalischen, sozialen, psychischen, professionellen und/oder kulturellen Zustand einer Person in ihrer Beziehung zu einem System. Mit dieser Thematik beschaeftigten sich 17 Fachbeitraege auf einer Arbeitstagung.
Deutsche Forschungsanstalt fuer Luft- und Raumfahrt e.V. (DLR), Koeln (Germany). Inst. fuer Flugmedizin   +2 more
core  

RECENT APPLICATIONS OF SEISMIC ISOLATION IN ITALY

open access: yes, 2019
This paper presents a state-of-the-art on seismic isolation in Italy and the most important applications. Those to new strategic and public buildings are shown, as well as to new residential buildings, pointing out the very good behavior shown by the ...
Martelli, A.   +3 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

3-Difluoromethyl-5-[4-(trifluoromethyl)phenyl]isoxazole

open access: yesIUCrData, 2018
The title molecule, C11H6F5NO, lies on a mirror plane in the orthorhombic unit cell, with only two F atoms each of the difluoro and trifluoromethyl substituents lying out of the plane.
Hui Zhao
doaj   +1 more source

Preliminary design of a test rig for combining passive nonlinear isolation with active control

open access: yes, 2012
Resilient elements are typically used to isolate delicate equipment from a vibrating host structure. Conventionally, these isolators are designed to operate in their linear region, but more recently nonlinear isolators have been employed to increase the ...
Waters, T.P., Rustighi, E., Ab Rahim, M.
core  

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