Results 81 to 90 of about 2,248,440 (315)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Identity Reconstruction as a Coping Mechanism in Addiction Recovery: A Pilot Stratified Randomized Controlled Trial of Narrative Therapy Group Intervention

open access: yesEuropean Journal of Investigation in Health, Psychology and Education
Relapse in substance use disorders remains a persistent clinical challenge. Identity reconstruction, the psychological transition from an internalized “addict” identity to a recovery-oriented self, may be a core coping mechanism for abstinence ...
Peipei Wang   +8 more
doaj   +1 more source

Foraminiferal ecology of contemporary isolation basins in Northwest Scotland [PDF]

open access: yes, 2002
Isolation basins contain high-resolution records of environmental change relating to RSL and climate since the last glacial maximum, and provide valuable data in constraining regional and global ice sheet and earth rheology models.
Laidler, Philip Damien
core  

UNDERSTANDING THE PHENOMENON OF PROFESSIONAL ISOLATION IN THE EARLY CHILDHOOD EDUCATION SECTOR [PDF]

open access: yes, 2022
My doctoral dissertation considers the phenomenon of professional isolation in the Early Childhood Education sector. Prior to the research study, I reviewed previous inquiries that explored the concepts of quality, retention issues, career satisfaction ...
Lindsey-Armstrong, Ruth
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Comparative analysis of C-Reactive protein levels among Non-comorbid, Comorbid, and Multimorbid Hospitalized COVID-19 patients

open access: yesBMC Infectious Diseases
Background C-reactive protein (CRP) is one of the most commonly monitored inflammatory markers in patients with COVID-19 to gain insight into the inflammation level in the body and to adopt effective disease management and therapeutic strategies.
Maria Shoukat   +12 more
doaj   +1 more source

Thermal Evolution near Heat-Generating Nuclear Waste Canisters Disposed in Horizontal Drillholes

open access: yesEnergies, 2019
We consider the disposal of spent nuclear fuel and high-level radioactive waste in horizontal holes drilled into deep, low-permeable geologic formations using directional drilling technology.
Stefan Finsterle   +4 more
doaj   +1 more source

Shock isolation using switchable stiffness

open access: yes, 2008
This study investigates a novel stiffness control strategy applied to the problem of shock isolation. This is based on the principle that the stiffness and mass are the principal physical properties that control the passive system shock response.
Ledezma Ramirez, Diego Francisco
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Dynamic analysis of high static low dynamic stiffness vibration isolation mounts [PDF]

open access: yes, 2013
The high static low dynamic stiffness (HSLDS) concept is a design strategy for an anti-vibration mount that seeks to increase isolation by lowering the natural frequency of the mount, whilst maintaining the same static load bearing capacity.
Neild, S.A.   +5 more
core   +1 more source

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