Results 101 to 110 of about 2,248,440 (315)

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Fault detection and isolation of actuator failures for a large transport aircraft

, 2007
- We consider the problem of designing residual generators with least dynamical orders to solve actuator fault detection and isolation problems for a Boeing 747-100/200 aircraft. The main result of our analysis is the proof of feasibility of the complete
Varga, Andreas
core  

Waste Isolation Pilot Plant 2001 Site Environmental Report [PDF]

, 2002
The United States (U.S.) Department of Energy's (DOE) Carlsbad Field Office (CBFO) and Westinghouse TRU Solutions LLC (WTS) are dedicated to maintaining high quality management of Waste Isolation Pilot Plant (WIPP) environmental resources. DOE Order 5400.
Westinghouse TRU Solutions, Inc.
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Material Testing for Physicists: Unraveling the Dissipative Nature of Silicone Elastomers via Ball Drop Testing

Macromolecular Materials and Engineering
Isaac Newton once contemplated the fall of an apple, setting in motion a revolution in the understanding of gravity. In a similar spirit of curiosity and inquiry, here a journey is embarked upon to explore the intricate world of viscoelastic damping for ...
Rene Preuer, Carina Emminger, Umut Cakmak, Ingrid Graz   +3 more
doaj   +1 more source

Isolation-By-Distance test for all cultivated and wild accessions.

, 2016
Testing Isolation-By-Distance (IBD) by plotting pairwise geographic distances against pairwise FST (left) and pairwise genetic distances (D) (right) for each pair of accessions genotyped in the all cultivated and wild accessions.
Wanda Viegas (81364), Manuela Silva (81359), Hugo R. Oliveira (164384), Susana Lopes (839057), Maria Manuela Veloso (2742799), Diana Tomás (2742802)   +5 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Decentralised control for multi-channel active vibration isolation (in special Issue on dynamics and control of smart structures)

, 2001
This paper describes a theoretical and experimental investigation into an active four-mount vibration isolation system, in which electromagnetic actuators are installed in parallel with each of the four passive mounts placed between a three-dimensional ...
Brennan, M.J., Kim, Sang-Myeong, Elliott, S.J.   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Exploring the relationship between cue-induced craving and withdrawal craving in MUD individuals based on a virtual-reality cue exposure paradigm

BMC Psychiatry
Background This study developed a virtual reality (VR) drug cue exposure paradigm for individuals with methamphetamine use disorder (MUD) to investigate the characteristics of withdrawal craving and cue-induced craving and their relationship.
Qiuping Huang, Xinxin Chen, Ying Tang, Xuhao Wang, Wenwu Wang, Li Chao, Yiqi Nie, Shihua Peng, Lin Zhao, Hongxian Shen, Zhenjiang Liao   +10 more
doaj   +1 more source