Results 121 to 130 of about 774,918 (251)
Identification of safety-relevant radionuclides for performance assessment modeling
Frontiers in Nuclear EngineeringWe propose, apply, and verify a screening approach for the selection of safety-relevant radionuclides that should be tracked in models assessing the performance of geologic repositories for the disposal of spent nuclear fuel and high-level radioactive ...
Stefan Finsterle +2 more
doaj +1 more source
Mind, 2018 Intellectualism is the widespread view that practical reason is a species of theoretical reason, distinguished from others by its objects: reasons to act. I argue that if practical reason is a species of theoretical reason, practical judgments by nature have nothing to do with action.
openaire +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Research on drug addiction detection based on AR-TSNET with bimodal EEG–NIRS
BioMedical Engineering OnLineTraditional research on drug addiction assessment relies primarily on psychological scales, self-reports from drug users, and subjective judgments from doctors, ands lacks objective physiological indicators and quantitative evaluation.
Xiaowen Zhang +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
On designing least order residual generators for fault detection and isolation [PDF]
, 2007 This paper addresses the problem of designing residual generators with least dynamical order to solve a class of fault detection and isolation problems.
Varga, Andreas
core
Isolation-By-Distance test for all cultivated and wild accessions.
, 2016 Testing Isolation-By-Distance (IBD) by plotting pairwise geographic distances against pairwise FST (left) and pairwise genetic distances (D) (right) for each pair of accessions genotyped in the all cultivated and wild accessions.
Wanda Viegas (81364) +5 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
RECENT APPLICATIONS OF SEISMIC ISOLATION IN ITALY
, 2019 This paper presents a state-of-the-art on seismic isolation in Italy and the most important applications. Those to new strategic and public buildings are shown, as well as to new residential buildings, pointing out the very good behavior shown by the ...
Martelli, A. +3 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source