Results 241 to 250 of about 4,752,749 (328)

<i>Candida auris</i> in Heart Transplant Donor: First Isolation in a Southern Italy Heart Transplant Center. [PDF]

Clin Case Rep
Giovannico L, Fischetti G, Savino L, Caggiano G, Chironna M, Tafuri S, Bottio T.   +6 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Patients with infectious TB who resist and refuse isolation in wards in Japan, 2022-2024. [PDF]

Public Health Action
Nagata Y, Ota M, Zama T, Hirao S.
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

COVID-19 stress, aggressiveness, and deviant behaviour: a mediation analysis of youth in the pandemic era. [PDF]

Aust J Psychol
Uvelli A, Floridi M, Guarino A, Tonini B, Prati G, Casale S, Masti A, Gualtieri G, Ferretti F.   +8 more
europepmc   +1 more source

Existential isolation [PDF]

Palliative and Supportive Care, 2017
openaire   +2 more sources

Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins

, 1998
Paul E. Mead, Yi Zhou, Kevin D. Lustig, Tara L. Huber, Marc W. Kirschner, Leonard I. Zon   +5 more
openalex   +2 more sources

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Psychometric properties of the social isolation and social network scale in community-dwelling older adults: Construct validity, reliability, and sensitivity. [PDF]

PLoS One
Park KH, Ha SK.
europepmc   +1 more source