Results 311 to 320 of about 1,777,918 (381)

Identification of Natural Isonitriles Through Ligation to an Azomethine Imine Probe

open access: yesChemistry – A European Journal, EarlyView.
The azomethine imine (AMI)–isonitrile (NC) ligation allowed for the chemoselective detection of natural isonitriles in bacteria and fungi. The reactivity‐based screening establishes a new stereogenic center, thereby allowing for facile distinction between chiral and achiral isonitriles. The work also unraveled a unique reactivity of isonitriles bearing
Maurice P. Biedermann   +6 more
wiley   +1 more source

TimeFlow 2: An Unsupervised Cell Lineage Detection Method for Flow Cytometry Data

open access: yesCytometry Part A, EarlyView.
TimeFlow 2 is a new method for cell lineage inference in flow cytometry data. It constructs cell state paths along pseudotime and aggregates them into biologically informative groups. It allows tracking of cytometry markers within each automatically inferred lineage.
Margarita Liarou   +2 more
wiley   +1 more source

Label‐Free Holographic Imaging Flow Cytometry With Deep‐Learning‐Based Detection and Classification of Thousands of Cells Per Second

open access: yesCytometry Part A, EarlyView.
ABSTRACT We present a new end‐to‐end neural network approach for real‐time biological cell detection and classification via label‐free quantitative imaging flow cytometry based on digital holography, offering a comprehensive representation of cellular structures without the need for chemical cell staining. In contrast to previous studies, our method is
Dana Yagoda‐Aharoni   +3 more
wiley   +1 more source

Imaging Flow Cytometry Detection of Cytogenetic Abnormalities in Circulating CD34+ Cells Predicts Leukemic Transformation in Myelofibrosis

open access: yesCytometry Part A, EarlyView.
ABSTRACT Myelofibrosis is a myeloproliferative neoplasm with potential to transform to acute myeloid leukemia. This evolution is unpredictable and current assays lack the sensitivity and applicability needed to predict this transformation. While population‐level data utilizing comprehensive genomic profiling can identify subgroups at higher risk of ...
Ruby M. Hamilton   +8 more
wiley   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

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