Results 131 to 140 of about 102,137 (247)

The Curious Case of CysE: Diversity and Distribution of Serine Acetyltransferases in Bacteria

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Serine acetyltransferase (CysE) is a member of the left‐handed β‐helix family of acetyltransferases that catalyze the rate limiting step in de novo cysteine biosynthesis. There are two isoforms of CysE that differ in length, with the shorter isoform lacking approximately 76 amino acids at the N‐terminus of the protein from the serine ...
Keely E. A. Oldham, Adele K. Williamson, Emily K. Grout, Joanna L. Hicks   +3 more
wiley   +1 more source

Nutritional Management in Severe Methylmalonic and Propionic Acidemias: How Much Medical Food Is Too Much? [PDF]

J Inherit Metab Dis
Margoses D, Imbard A, Pontoizeau C, Brassier A, Arnoux JB, Bouchereau J, Bérat CM, Assoun M, Belloche C, Dewulf S, Dubois S, Samba B, Servais A, Dao M, Le Guillou E, de Colnet A, Ottolenghi C, de Lonlay P, Benoist JF, Schiff M.   +19 more
europepmc   +1 more source

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler, Elise Glattard, Nicolas Arnaud, Johana Chicher, Philippe Hammann, Emmanuelle Leize‐Wagner, Burkhard Bechinger, Noelle Potier   +7 more
wiley   +1 more source

Deciphering a missing piece of the branched-chain amino acids uptake puzzle: YhjE is an L-isoleucine and L-valine transporter in <i>Escherichia coli</i> K-12. [PDF]

Front Microbiol
Molev SV, Stepanova AA, Vybornaya TV, Khozov AA, Surkov MM, Badun GA, Chernysheva MG, Netrusov AI, Yanenko AS, Sineoky SP, Bubnov DM.   +10 more
europepmc   +1 more source

Development of a Novel Polyleucine‐Based Immunopotentiator for Subunit Vaccines Against Group A Streptococcus

Small, EarlyView.
Self‐assembling amphiphilic peptide L15K6 is used as a novel immunoadjuvant for the development of a Group A Streptococcus vaccine. Robust antigen‐specific IgG responses are generated and manage to kill isolated strains of Group A Streptococcus. Cellular and bulk RNA sequencing data reveals that L15K6 regulates immune responses potentially through TLR ...
Lantian Lu, Jazmina L. Gonzalez Cruz, Rabina Giri, Yuexiao Zhang, Sahra Bashiri, Leslie C. Domínguez Cadena, Shuhang Li, Zeinab G. Khalil, Waleed M. Hussein, Jingwen Wang, Jolynn Kiong, Xuehan Lu, Jiahui Zhang, Miao Lu, Wenbin Huang, Wei Yang Kong, Ummey Jannatun Nahar, Prashamsa Koirala, Zhong Guo, Patricia Walden, Antje Blumenthal, Jakob Begun, Kirill Alexandrov, Istvan Toth, Rachel J. Stephenson, Mariusz Skwarczynski   +25 more
wiley   +1 more source

Contrasting effects of glutamate and branched-chain amino acid metabolism on acid tolerance in a <i>Castellaniella</i> isolate from acidic groundwater. [PDF]

Appl Environ Microbiol
Goff JL, Durrence KL, Thorgersen MP, Trotter VV, Chen Y, Kosina SM, Wang ALW, Poole FL, Northen TR, Petzold CJ, Deutschbauer AM, Adams MWW.   +11 more
europepmc   +1 more source

Self‐Healing and pH‐Robust Hydrogels Enabled by Synergistic Supramolecular Interactions for Injectable Gastrointestinal Wound Repair

Small, EarlyView.
A pH‐robust injectable hydrogel enabled by synergistic supramolecular interactions is developed to address the intrinsic limitations of conventional hydrogel dressings in complex gastrointestinal environments. By actively leveraging environmental stimuli to regulate functionality, this supramolecular synergy strategy provides a versatile platform for ...
Li Xiang, Lei Liu, Shixin Zhang, Yuhao Zhang, Ziqian Zhao, Jiangwei Chen, Jiawen Zhang, Jingyi Hu, Yunfei Chen, Hongbo Zeng   +9 more
wiley   +1 more source

Causal effects and metabolite mediation of immune cells in preterm birth: a Mendelian randomization study. [PDF]

Am J Clin Exp Immunol
Zhou T, Zhang Y, Zhang S, Cao J, Feng B, Jin J, Tang Q, Qiu J, Qiao L, Liang Y.   +9 more
europepmc   +1 more source

Exploring the Impact of Polystyrene Microplastic Beads on Male Gonads of the Marine Mussel, Mytilus galloprovincialis

Environmental Toxicology, EarlyView.
ABSTRACT Plastic, with its remarkable versatility and numerous applications, has greatly benefited humanity. However, its extreme resistance to natural degradation means it persists in the environment for long periods, causing global environmental problems.
Teresa Chianese, Mariachiara Galati, Tiziana Cappello, Maria Maisano, Gennaro Lettieri, Carmela Marinaro, Marina Piscopo, Gianluca Fasciolo, Carlos Gravato, Gaetana Napolitano, Giulia Paolella, Annamaria Locascio, Rosaria Scudiero, Luigi Rosati   +13 more
wiley   +1 more source

HPLC-DAD analysis of functional dietary supplements followed by liquid-liquid microextraction-assisted FTIR identification of IR-active ingredients. [PDF]

Sci Rep
Pavelek D, Kaykhaii M, Jampilek J, Halko R.   +3 more
europepmc   +1 more source