Results 211 to 220 of about 183,864 (337)

Targeting emerging amino acid dependencies and transporters in cancer therapy. [PDF]

Front Pharmacol
Akinlalu A, Ogberefor E, Gao T, Sun D.
europepmc   +1 more source

Leveraging Viscosity to Unlock the Osteogenic Potential of BMP‐2 Mimetic DWIVA

Small, EarlyView.
Dynamic interfaces based on supported lipid bilayers demonstrate that the osteogenic potential of the BMP‐2 mimetic DWIVA can be harnessed by modulating substrate viscosity. This work highlights that the viscous properties of the cellular microenvironment play a crucial role in the mechanosensitive regulation of growth factor activity.
Finlay Cunniffe, Ziyuan Luo, Eva Barcelona‐Estaje, Eva Forrest, Manuel Salmeron‐Sanchez, Marco Cantini   +5 more
wiley   +1 more source

Assessment of genetic and metabolite associations of branched chain amino acids with metabolic disease in the UK Biobank using Mendelian randomization. [PDF]

BMC Med Genomics
Konarkowski J, Astore C, Gibson G.
europepmc   +1 more source

Enhancement of the bioavailability of cinnarizine from its .BETA.-cyclodextrin complex on oral administration with L-isoleucine as a competing agent.

, 1986
Tadakazu Tokumura, Yuki Tsushima, Kimio Tatsuishi, Masanori Kayano, Yoshiharu Machida, Tsuneji Nagai   +5 more
openalex   +2 more sources

Mutational analysis of isoleucine-valine biosynthesis in Saccharomyces cerevisiae. Mapping ofilv2 andilv5 [PDF]

, 1983
Jens G. Litske Petersen, Morten C. Kielland‐Brandt, Steen Holmberg, Torsten Nilsson‐Tillgren   +3 more
openalex   +1 more source

Renovating Neural Networks With Viral‐Mediated Gene Transfer From A Tissue Contacting Matrix Mimic

Small, EarlyView.
Fmoc‐DDIKVAV self‐assembling peptidemediated delivery of AAV‐BDNF significantly enhances neuroprotection in the striatum of a mouse model compared with AAV‐BDNF injection alone. This synergistic integration of biomaterial scaffolding and gene therapy holds substantial promise for slowing the progression of neurodegenerative diseases such as Huntington ...
Shiva Soltani Dehnavi, Negar Mahmoudi, Yi Wang, Samuel Cheeseman, Rita Ferreira, Ross D. Hannan, Leszek Lisowski, Vincent S. J. Craig, Niamh Moriarty, Clare L. Parish, Richard J. Williams, David R. Nisbet   +11 more
wiley   +1 more source

Dietary Branched-Chain Amino Acids and Hyper-LDL-Cholesterolemia: A Case-Control Study Using Interpretable Machine-Learning Models in Chinese Children and Adolescents. [PDF]

Nutrients
Zang Z, Zhang S, Liu C, Liu Y, Tian M, Luo X, Zhu Q, Liu L, Yu L.   +8 more
europepmc   +1 more source

Comparative study of the structural and physicochemical properties of two food derived antihypertensive tri-peptides, Isoleucine-Proline-Proline and Leucine-Lysine-Proline encapsulated into a chitosan based nanoparticle system

, 2017
Minna K. Danish, Giuliana Vozza, Hugh J. Byrne, Jesús M. Frías, Sinéad M. Ryan   +4 more
openalex   +2 more sources

Exploring the Impact of Polystyrene Microplastic Beads on Male Gonads of the Marine Mussel, Mytilus galloprovincialis

Environmental Toxicology, EarlyView.
ABSTRACT Plastic, with its remarkable versatility and numerous applications, has greatly benefited humanity. However, its extreme resistance to natural degradation means it persists in the environment for long periods, causing global environmental problems.
Teresa Chianese, Mariachiara Galati, Tiziana Cappello, Maria Maisano, Gennaro Lettieri, Carmela Marinaro, Marina Piscopo, Gianluca Fasciolo, Carlos Gravato, Gaetana Napolitano, Giulia Paolella, Annamaria Locascio, Rosaria Scudiero, Luigi Rosati   +13 more
wiley   +1 more source

Dietary isoleucine content modulates the metabolic and molecular response to a Western diet in mice. [PDF]

Mol Metab
Trautman ME, Green CL, MacArthur MR, Chaiyakul K, Alam YH, Yeh CY, Babygirija R, James I, Gilpin M, Zelenovskiy E, Green M, Marshall RN, Raskin A, Sonsalla MM, Flores V, Simcox JA, Ong IM, Malecki KC, Jang C, Lamming DW.   +19 more
europepmc   +1 more source