Results 91 to 100 of about 90,505 (292)

Lipid‐associated macrophages are more abundant in subcutaneous than visceral adipose tissue in patients with obesity

Obesity, EarlyView.
Abstract Objective Because white adipose tissue is infiltrated by several immune cells and their signature in individuals with obesity has not been fully characterized, we wanted to study the most abundant population, which is macrophages, a subtype of myeloid cell. Methods To address this objective, we performed transcriptomic analysis of subcutaneous
Marjorie Reyes‐Farias, Pablo Fernández‐García, Patricia Corrales, Lorena González, David Navarro‐Sanagustín, Andrea Soria‐Gondek, Silvia Pellitero, Jordi Tarascó, Pau Moreno, José M. Balibrea, Laia Gatell, Lauro Sumoy, María Galán, Ester Martínez, Francesc Villarroya, Rubén Cereijo, Laura Herrero, David Sánchez‐Infantes   +17 more
wiley   +1 more source

Essential Oil Profiles of Lippia turbinata (Verbenaceae) from Argentina: Insights from a Systematic Review and Meta‐Analysis

ChemistryOpen, EarlyView.
This study systematically reviews essential oil (EO) profiles of Lippia turbinata (Verbenaceae) populations from Argentina. A meta‐analysis reveals significant chemical variability and distinct chemotypes, primarily defined by limonene, carvone, β‐caryophyllene, and caryophyllene oxide.
Fernando Livio Corzo, Franco Emmanuel Calvo, Emilio Fernando Lizarraga, Guillermo Emilio Marcial, Maria Ines Mercado   +4 more
wiley   +1 more source

Prolyl isomerases in gene transcription

Biochimica et Biophysica Acta (BBA) - General Subjects, 2015
Peptidyl-prolyl isomerases (PPIases) are enzymes that assist in the folding of newly-synthesized proteins and regulate the stability, localization, and activity of mature proteins. They do so by catalyzing reversible (cis-trans) rotation about the peptide bond that precedes proline, inducing conformational changes in target proteins.This review will ...
openaire   +3 more sources

Covalent Inhibition of the Peptidyl‐Prolyl Isomerase Pin1 by Sulfopin Results in a Broad Impact on the Phosphoproteome of Human Osteosarcoma U2‐OS Cells

PROTEOMICS, EarlyView.
ABSTRACT Peptidyl‐prolyl isomerase, NIMA‐interacting protein 1‐(Pin1) catalyses the cis–trans interconversion of the inflexible bond between serine or threonine residues and proline at the +1 position (pSer/pThr‐Pro). Although initially discovered as an essential regulator of cell division, Pin1 has since been identified as a regulator of many ...
Scott E. Roffey, Owen Hovey, Kristina Jurcic, Kun Ping Lu, Xiao Zhen Zhou, David W. Litchfield   +5 more
wiley   +1 more source

Bacterial Chaperone Domain Insertions Convert Human FKBP12 into an Excellent Protein-Folding Catalyst—A Structural and Functional Analysis

Molecules
Many folding enzymes use separate domains for the binding of substrate proteins and for the catalysis of slow folding reactions such as prolyl isomerization. FKBP12 is a small prolyl isomerase without a chaperone domain.
Gabriel Žoldák, Thomas A. Knappe, Anne-Juliane Geitner, Christian Scholz, Holger Dobbek, Franz X. Schmid, Roman P. Jakob   +6 more
doaj   +1 more source

In Silico Prediction of T and B Cell Epitopes of Der f 25 in Dermatophagoides farinae

International Journal of Genomics, 2014
The house dust mites are major sources of indoor allergens for humans, which induce asthma, rhinitis, dermatitis, and other allergic diseases. Der f 25 is a triosephosphate isomerase, representing the major allergen identified in Dermatophagoides farinae.
Xiaohong Li, Hai-Wei Yang, Hao Chen, Jing Wu, Yehai Liu, Ji-Fu Wei   +5 more
doaj   +1 more source

The active centre of triose phosphate isomerase [PDF]

, 1966
PM Burton, S G Waley
openalex   +1 more source

Defining the Molecular Impacts of Humalite Application on Field‐Grown Wheat (Triticum aestivum L.) Using Quantitative Proteomics

PROTEOMICS, EarlyView.
ABSTRACT Increasing global food production demands have resulted in increased fertilizer usage, causing detrimental environmental impacts. Biostimulants, such as humic substances, are currently being applied as a strategy to increase plant nutrient‐use efficiency and minimize environmental impacts within cropping systems.
Lauren E. Grubb, Mohana Talasila, Linda Y. Gorim, Richard Glen Uhrig   +3 more
wiley   +1 more source

Phosphoglucose isomerase variation in man [PDF]

, 1968
Linda I. Fitch, Christian Parr, S.G. Welch   +2 more
openalex   +1 more source

Fecal Metaproteomics as a Tool to Monitor Functional Modifications Induced in the Gut Microbiota by Ketogenic Diet: A Case Study

PROTEOMICS, EarlyView.
ABSTRACT Metaproteomics is a valuable approach to characterize the biological functions involved in the gut microbiota (GM) response to dietary interventions. Ketogenic diets (KDs) are very effective in controlling seizure severity and frequency in drug‐resistant epilepsy (DRE) and in the weight loss management in obese/overweight individuals.
Alessandro Tanca, Simona Masia, Piero Giustacchini, Sergio Uzzau   +3 more
wiley   +1 more source