Results 101 to 110 of about 98,929 (291)

Taxonomic and functional shifts in the microbiome of severely obese, prediabetic patients: Ketogenic diet versus energy‐matched standard diet

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Obesity and type 2 diabetes mellitus (T2DM) are among the leading global health challenges of the 21st century. While caloric restriction remains the cornerstone of weight loss interventions, ketogenic diets (KD), characterised by low carbohydrate and high fat intake, have been shown to improve metabolic health partly by modulating the ...
June Stone   +5 more
wiley   +1 more source

Update on diagnosis, nonpharmacological treatment and prevention of Equine Gastric Ulcer Syndrome (EGUS)

open access: yesEquine Veterinary Education, EarlyView.
Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley   +1 more source

Three-dimensional structure and domain-domain interactions of protein disulfide isomerase as revealed by NMR spectroscopy

open access: diamond, 2003
Michiko Nakano   +8 more
openalex   +2 more sources

Disequilibrium in the triose phosphate isomerase system in rat liver [PDF]

open access: bronze, 1969
Richard L. Veech   +3 more
openalex   +1 more source

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

open access: yesThe FEBS Journal, EarlyView.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

Structure-Activity Relationships for Inhibition of Type 1 and 2 Human 5.alpha.-Reductase and Human Adrenal 3.beta.-Hydroxy-.DELTA.5-steroid Dehydrogenase/3-Keto-.DELTA.5-steroid Isomerase by 6-Azaandrost-4-en-3-ones: Optimization of the C17 Substituent

open access: green, 1995
Stephen V. Frye   +20 more
openalex   +1 more source

Phycocyanobilin biosynthesis in Galdieria sulphuraria requires isomerization of phycoerythrobilin synthesized by bilin reductases

open access: yesThe FEBS Journal, EarlyView.
The biosynthesis of bilins, tetrapyrroles essential for light harvesting and sensing, is performed by specific enzymes (FDBRs). In Galdieria sulphuraria, both phycobiliprotein types bind phycocyanobilin, despite lacking the canonical synthesizing gene PCYA. Instead, PEBA and PEBB are encoded, producing phycoerythrobilin, proposed to be later isomerized
Federica Frascogna   +4 more
wiley   +1 more source

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