Results 121 to 130 of about 168,780 (336)
Hereditary Hemolytic Anemia Associated with Glucosephosphate Isomerase (GPI) Deficiency— a New Enzyme Defect of Human Erythrocytes [PDF]
, 1968 Marjorie A. Baughan +5 more
openalex +1 more source
New insights into applications of base editor in hereditary disorders
Interdisciplinary Medicine, EarlyView.Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai +8 more
wiley +1 more source
Principal basis for enzyme power [PDF]
, 2008 The reaction rate enhancement that enzymes produce had not been fully appreciated. The object of the article is to present the mechanism of the enormous catalytic power of the enzymes.
Alexander G. Foigel
core +1 more source
Thermostable Isomerase Processes for Biotechnology
, 2017 Isomers are molecules with identical atomic composition but with different structural and/or functional characteristics. Isomerases are the enzymes catalyzing the conversion between different isomeric forms of a variety of molecules (Figure 1). Thermostable isomerases have the potential to withstand harsh industrial process conditions, including ...
González Grau, Juan Miguel +10 more
openaire +4 more sources
Telomere‐Related Gene Networks in the Ovary Shift Across Environmental Factors
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.ABSTRACT The ovary is key to linking environmental factors with the timing and quality of offspring development. Focused on free‐living female tree swallows (Tachycineta bicolor), we measured temporal variation in ovarian expression of genes involved in the regulation of telomere length.
Sarah E. Wolf +3 more
wiley +1 more source
Disequilibrium in the triose phosphate isomerase system in rat liver [PDF]
, 1969 Richard L. Veech +3 more
openalex +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley +1 more source
Prolyl isomerases in gene transcription
Biochimica et Biophysica Acta (BBA) - General Subjects, 2015 Peptidyl-prolyl isomerases (PPIases) are enzymes that assist in the folding of newly-synthesized proteins and regulate the stability, localization, and activity of mature proteins. They do so by catalyzing reversible (cis-trans) rotation about the peptide bond that precedes proline, inducing conformational changes in target proteins.This review will ...
openaire +3 more sources
mLife, EarlyView.Abstract Aeromonas hydrophila, an opportunistic pathogen, often encodes Type VI Secretion System (T6SS) genes. However, the specific functions of T6SS, particularly in the context of clinical strains, remain poorly understood. In this study, we characterize a multi‐drug‐resistant strain, AH54, which possesses a complete and functional T6SS, composed of
Hao Wang +6 more
wiley +1 more source
In Silico Prediction of T and B Cell Epitopes of Der f 25 in Dermatophagoides farinae
International Journal of Genomics, 2014 The house dust mites are major sources of indoor allergens for humans, which induce asthma, rhinitis, dermatitis, and other allergic diseases. Der f 25 is a triosephosphate isomerase, representing the major allergen identified in Dermatophagoides farinae.
Xiaohong Li +5 more
doaj +1 more source