Results 21 to 30 of about 168,780 (336)

Evolution of substrate specificity in a retained enzyme driven by gene loss. [PDF]

open access: yes, 2017
The connection between gene loss and the functional adaptation of retained proteins is still poorly understood. We apply phylogenomics and metabolic modeling to detect bacterial species that are evolving by gene loss, with the finding that ...
Babnigg, Gyorgy   +14 more
core   +1 more source

Glutathione Transferases as Efficient Ketosteroid Isomerases

open access: yesFrontiers in Molecular Biosciences, 2021
In addition to their well-established role in detoxication, glutathione transferases (GSTs) have other biological functions. We are focusing on the ketosteroid isomerase activity, which appears to contribute to steroid hormone biosynthesis in mammalian ...
Bengt Mannervik   +4 more
doaj   +1 more source

NmPin from the marine thaumarchaeote Nitrosopumilus maritimus is an active membrane associated prolyl isomerase. [PDF]

open access: yes, 2016
We cordially thank Alma Rute for excellent technical assistance and the DFG (GRK 1431-1 and 1431-2) for financial support (PB). We thank the Microscope and Histology Facility of the University of Aberdeen for providing their equipment.
Bayer, Peter   +5 more
core   +2 more sources

Comparing the xylose reductase/xylitol dehydrogenase and xylose isomerase pathways in arabinose and xylose fermenting Saccharomyces cerevisiae strains

open access: yesBiotechnology for Biofuels, 2008
Background Ethanolic fermentation of lignocellulosic biomass is a sustainable option for the production of bioethanol. This process would greatly benefit from recombinant Saccharomyces cerevisiae strains also able to ferment, besides the hexose sugar ...
Hahn-Hägerdal Bärbel   +2 more
doaj   +1 more source

Artificial Photosynthesis Would Unify the Electricity-Carbohydrate-Hydrogen Cycle for Sustainability [PDF]

open access: yes, 2010
Sustainable development requires balanced integration of four basic human needs – air (O2/CO2), water, food, and energy. To solve key challenges, such as CO2 fixation, electricity storage, food production, transportation fuel production, water ...
Yi-Heng Percival Zhang
core   +2 more sources

Comparison of the Recombinant Glucosephosphate Isomerase from Different Zymodemes of Entamoeba histolytica with Their Natural Counterparts by Isoenzyme Electrophoresis [PDF]

open access: yesIranian Journal of Public Health, 2005
Entamoeba histolytica is the etiological agent of invasive amoebiasis, the third leading parasitic cause of mortality in the world. Our aim was to find a molecular correlation between a glucosephosphate isomerase zymodeme analyses in E.
E Razmjou   +6 more
doaj   +1 more source

Structure-based directed evolution improves S. cerevisiae growth on xylose by influencing in vivo enzyme performance

open access: yesBiotechnology for Biofuels, 2020
Background Efficient bioethanol production from hemicellulose feedstocks by Saccharomyces cerevisiae requires xylose utilization. Whereas S. cerevisiae does not metabolize xylose, engineered strains that express xylose isomerase can metabolize xylose by ...
Misun Lee   +4 more
doaj   +1 more source

Protein disulphide isomerase inhibition as a potential cancer therapeutic strategy

open access: yesCancer Medicine, 2021
The protein disulphide isomerase (PDI) gene family is a large, diverse group of enzymes recognised for their roles in disulphide bond formation within the endoplasmic reticulum (ER).
Lauren E. Powell, Paul A. Foster
doaj   +1 more source

Influence of ellagitannins extracted by pomegranate fruit on disulfide isomerase PDIA3 activity [PDF]

open access: yes, 2019
Pomegranate fruit is a functional food of high interest for human health due to its wide range of phytochemicals with antioxidant properties are implicated in the prevention of inflammation and cancer. Ellagitannins, such as punicalagin and ellagic acid,
Altieri, Fabio   +6 more
core   +1 more source

Protein disulphide isomerase [PDF]

open access: yesCurrent Biology, 2003
What is it? Protein disulphide isomerase is an enzyme with two interrelated activities: as an oxidoreductase, it can catalyse the formation, reduction and isomerisation of disulphide bonds; and as a polypeptide binding protein, it can function as a molecular chaperone which assists the folding of polypeptides.
openaire   +2 more sources

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