Results 61 to 70 of about 196,977 (320)

Evaluation of NV556, a Novel Cyclophilin Inhibitor, as a Potential Antifibrotic Compound for Liver Fibrosis

open access: yesCells, 2019
Hepatic fibrosis can result as a pathological response to nonalcoholic steatohepatitis (NASH). Cirrhosis, the late stage of fibrosis, has been linked to poor survival and an increased risk of developing hepatocellular carcinoma, with limited treatment ...
Sonia Simón Serrano   +12 more
doaj   +1 more source

Production of D-Allose From D-Allulose Using Commercial Immobilized Glucose Isomerase

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Rare sugars are regarded as functional biological materials due to their potential applications as low-calorie sweeteners, antioxidants, nucleoside analogs, and immunosuppressants.
Mi Na Choi   +6 more
doaj   +1 more source

Relationship between glycolysis and exopolysaccharide biosynhesis in Lactococcus lactis [PDF]

open access: yes, 2001
The relationships between glucose metabolism and exopolysaccharide (EPS) production in a Lactococcus lactis strain containing the EPS gene cluster (Eps ) and in nonproducer strain MG5267 (Eps) were characterized.
Ramos, A.   +3 more
core   +1 more source

Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations

open access: yesInternational Journal of Molecular Sciences, 2016
Prolyl isomerases are divided into three groups, the FKBP family, Cyclophilin and the Parvulin family (Pin1 and Par14). Among these isomerases, Pin1 is a unique prolyl isomerase binding to the motif including pSer/pThr-Pro that is phosphorylated by ...
Yusuke Nakatsu   +10 more
semanticscholar   +1 more source

Catalyzing Protein Folding by Chaperones

open access: yesBiology
Protein folding is a fundamental process essential for cellular growth and health, yet it is also susceptible to errors that can result in misfolding and disease.
Zijue Huang, Scott Horowitz
doaj   +1 more source

Metabolic engineering considerations for the heterologous expression of xylose-catabolic pathways in Saccharomyces cerevisiae.

open access: yesPLoS ONE, 2020
Xylose, the second most abundant sugar in lignocellulosic biomass hydrolysates, can be fermented by Saccharomyces cerevisiae expressing one of two heterologous xylose pathways: a xylose oxidoreductase pathway and a xylose isomerase pathway.
Deokyeol Jeong   +7 more
doaj   +1 more source

The small subunit 1 of the Arabidopsis isopropylmalate isomerase is required for normal growth and development and the early stages of glucosinolate formation. [PDF]

open access: yesPLoS ONE, 2014
In Arabidopsis thaliana the evolutionary and functional relationship between Leu biosynthesis and the Met chain elongation pathway, the first part of glucosinolate formation, is well documented. Nevertheless the exact functions of some pathway components
Janet Imhof   +6 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Inhibition of protein disulfide isomerase induces differentiation of acute myeloid leukemia cells

open access: yesHaematologica, 2018
A cute myeloid leukemia is a malignant disease of immature myeloid cells. Despite significant therapeutic effects of differentiation-inducing agents in some acute myeloid leukemia subtypes, the disease remains incurable in a large fraction of patients ...
Justyna Chlebowska-Tuz   +22 more
doaj   +1 more source

L-Arabinose Isomerase Formation in a Conditional Mutant of Gene \u3cem\u3earaA\u3c/em\u3e of \u3cem\u3eEscherichia coli\u3c/em\u3e B/r [PDF]

open access: yes, 1972
A temperature-sensitive mutant of Escherichia coli in which the synthesis of l-arabinose isomerase is blocked during growth at 42 C was found to possess the following properties.
Irr, Joseph   +2 more
core   +1 more source

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