Results 71 to 80 of about 90,505 (292)

Prolyl Isomerases and Nuclear Function [PDF]

open access: yesCell, 1998
The c-Myb/Cyp40 interaction raises the question of whether other transcription factors are regulated by PPIases. The only other example of a transcription factor that may be regulated by PPIase action is the zinc finger protein YY1, which interacts with CypA and FKBP12 (Yang et al. 1995xYang, W.M, Inouye, C.J, and Seto, E. J. Biol. Chem.
openaire   +3 more sources

Valorization of Apple Pomace: Production of Phloretin Using a Bacterial Cellulose‐Immobilized β‐Glycosidase

open access: yesChemSusChem, EarlyView.
This study presents a whole valorization of apple processing waste: phloretin is efficiently produced from phloridzin (abundantly found in apple residues), using a β‐glycosidase immobilized on bacterial cellulose in a biphasic system. Notably, bacterial cellulose is derived from fermentation of apple pomace sugars, making both the enzyme carrier and ...
Agostina Colacicco   +6 more
wiley   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

Application of Ferulic Acid to Alleviate Chilling Injury of Banana Fruit by Regulating Redox, Phenylpropanoid, and Energy Metabolism

open access: yesFood Frontiers, EarlyView.
This study investigated the effect of ferulic acid (FA) on the cold tolerance of banana fruit under 6°C‐storage for 7 days. In comparison with control, 3 mM FA treatment significantly alleviated chilling symptoms of banana fruit by enhancing phenylpropanoid metabolism and maintaining redox and energy homeostasis. ABSTRACT Banana fruit is susceptible to
Yu Hou   +9 more
wiley   +1 more source

Inhibition of the Activity of Cyclophilin A Impedes Prolactin Receptor-Mediated Signaling, Mammary Tumorigenesis, and Metastases

open access: yesiScience, 2020
Summary: Prolactin (PRL) and its receptor (PRLr) play important roles in the pathogenesis of breast cancer. Cyclophilin A (CypA) is a cis-trans peptidyl-prolyl isomerase (PPI) that is constitutively associated with the PRLr and facilitates the activation
Shawn Hakim   +3 more
doaj  

Dystroglycan is associated to the disulfide isomerase ERp57

open access: yesExperimental Cell Research, 2012
Dystroglycan (DG) is an extracellular receptor composed of two subunits, α-DG and β-DG, connected through the α-DG C-terminal domain and the β-DG N-terminal domain. We report an alanine scanning of all DG cysteine residues performed on DG-GFP constructs overexpressed in 293-Ebna cells, demonstrating that Cys-669 and Cys-713, both located within the β ...
Sciandra Francesca   +8 more
openaire   +5 more sources

A Multifaceted Review on Neodiosmin In Planta Distribution, (Bio)synthesis, Food and Health Effects

open access: yesFuture Postharvest and Food, EarlyView.
ABSTRACT Neodiosmin (NEO) is a major glycosylated flavone that is derived from the bitter flavanone neo‐hesperidin in citrus fruits including orange, lime, and lemon. One of the most important features of NEO is that it exerts a notable debittering effect on plant flavonoids justifying its wide use as a food additive.
Yuxuan Zhao   +4 more
wiley   +1 more source

Engineering xylose metabolism in thraustochytrid T18

open access: yesBiotechnology for Biofuels, 2018
Background Thraustochytrids are heterotrophic, oleaginous, marine protists with a significant potential for biofuel production. High-value co-products can off-set production costs; however, the cost of raw materials, and in particular carbon, is a major ...
Alexandra Merkx-Jacques   +10 more
doaj   +1 more source

Serum phosphohexose isomerase in cancer.II. As an index of tumor growth in metastatic carcinoma of the breast [PDF]

open access: bronze, 1954
Oscar Bodansky   +2 more
openalex   +1 more source

Clinical outcomes in an adult patient with mannose phosphate isomerase-congenital disorder of glycosylation who discontinued mannose therapy

open access: yesMolecular Genetics and Metabolism Reports, 2020
The mannose phosphate isomerase-congenital disorder of glycosylation (MPI-CDG) is caused by phosphomannose isomerase deficiency. Clinical features include hyperinsulinaemic hypoglycaemia, protein losing enteropathy, hepatomegaly and hepatic fibrosis ...
Kinza Noman   +6 more
doaj  

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