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Isoniazid Preventive Therapy and Risk for Resistant Tuberculosis [PDF]

Emerging Infectious Diseases, 2006
In the context of tuberculosis (TB) resurgence, isoniazid preventive therapy (IPT) is increasingly promoted, but concerns about the risk for development of isoniazid-resistant tuberculosis may hinder its widespread implementation.
Maria Elvira Balcells, Sara L. Thomas, Peter Godfrey-Faussett, Alison D. Grant   +3 more
doaj   +7 more sources

Isoniazid Preventive Therapy in Contacts of Multidrug-Resistant Tuberculosis. [PDF]

Am J Respir Crit Care Med, 2020
Abstract Rationale The World Health Organization recommends the use of isoniazid (INH) alone or in combination with rifapentine to treat latent tuberculosis infections. The recent rise of drug-resistant tuberculosis has complicated the choice of treatment regimen for latent tuberculosis ...
Huang CC, Becerra MC, Calderon R, Contreras C, Galea J, Grandjean L, Lecca L, Yataco R, Zhang Z, Murray M.   +9 more
europepmc   +9 more sources

Hyperglycaemia induced by isoniazid preventive therapy

Journal of Family Medicine and Primary Care, 2018
We report the case of a HIV-positive patient with type 2 diabetes mellitus who presented with uncontrolled blood sugars after the initiation of prophylactic isoniazid (INH) therapy.
Roshni Jhan Ganguly, Rahul R Abraham, Ramakrishna Prasad, Badakere C Rao   +3 more
doaj   +3 more sources

Pellagra in isoniazid preventive and antiretroviral therapy

IDCases, 2019
Pellagra is caused by cellular deficiency of niacin or its precursor amino acid, tryptophan. Isoniazid preventive therapy (IPT) is the administration of isoniazid (INH) to latent tuberculosis (TB) infection affected people preventing advancement to ...
John Koech Kipsang, Joseph K. Choge, Pamela A. Marinda, Christopher Khayeka-Wandabwa   +3 more
doaj   +3 more sources

Effect of isoniazid preventive therapy on tuberculosis incidence and its predictors among adult patients enrolled in antiretroviral therapy at public health facilities in Ambo Town, Oromia, Ethiopia: a retrospective cohort study [PDF]

BMC Infectious Diseases
Background Tuberculosis is one of the major causes of illness and death among people living with the human immunodeficiency virus. The World Health Organization has recommended isoniazid preventive therapy for those patients to decrease tuberculosis ...
Milkesa Tesfaye, Tolessa Beyene, Meseret Ifa, Seifadin Ahmed, Dachasa Dabalo   +4 more
doaj   +2 more sources

Formulation of dispersible isoniazid/pyridoxine fixed-dose combination tablets for isoniazid preventive therapy in pediatrics

Cogent Medicine, 2020
Objective: Oral dispersible isoniazid 50 mg/pyridoxine 6.25 mg fixed-dose combination (FDC) tablets were formulated for Isoniazid Preventive Therapy in pediatrics weighing less than 5 kg.
M. W. Mwangi, L. J. Tirop, P. M. Njogu, J. M. Bururia, N. M. Njuguna, E. G. Mbae   +5 more
doaj   +2 more sources

Prevalence and predictors of tuberculosis among HIV patients who completed isoniazid preventive therapy (IPT) at Reach out Mbuya community health initiative [PDF]

Scientific Reports, 2023
Tuberculosis (TB) continues to be the leading cause of morbidity and mortality among human immunodeficiency virus (HIV) infected individuals in Sub Saharan Africa, including Uganda.
Wycliff Sekayi, Edity Namyalo, Josephine Namayanja, Joseph M. Kungu   +3 more
doaj   +2 more sources

Isoniazid preventive therapy and tuberculosis transcriptional signatures in people with HIV. [PDF]

AIDS, 2022
Objective(s): To examine the association between isoniazid preventive therapy (IPT) or nontuberculous mycobacteria (NTM) sputum culture positivity and tuberculosis (TB) transcriptional signatures in people with HIV.
Valinetz ED, Matemo D, Gersh JK, Joudeh LL, Mendelsohn SC, Scriba TJ, Hatherill M, Kinuthia J, Wald A, Cangelosi GA, Barnabas RV, Hawn TR, Horne DJ.   +12 more
europepmc   +3 more sources

Factors associated with uptake of isoniazid preventive therapy among children living with HIV in Mwanza region, Tanzania: a cross-sectional study [PDF]

BMC Public Health
Background Tuberculosis (TB) is a leading cause of death among children living with HIV (CLHIV). Isoniazid preventive therapy (IPT) reduces the incidence of TB by 70% and mortality by 50% among CLHIV.
Ally Tuwa, David Okia, Ritah Nantale, Hyasinta Jaka, Jimmy Patrick Alunyo, David Mukunya, Joseph KB Matovu, Dan Kibuule   +7 more
doaj   +2 more sources

Evaluation Of Isoniazid Preventive Therapy Policy

National Journal of Community Medicine, 2012
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Bhavesh Modi, Paresh Dave
doaj   +1 more source