Results 71 to 80 of about 91,861 (319)

Caracterização funcional da hipertrofia miocárdica induzida pelo isoproterenol e de sua regressão

Arquivos Brasileiros de Cardiologia, 2001
OBJETIVO: Analisar as disfunções da hipertrofia miocárdica induzida pelo isoproterenol e de sua regressão. Corações isolados hipertrofiados por isoproterenol (ISO) (8 dias) e após 22 dias de sua suspensão (regressão) foram distendidos.
Neif Murad, Marcelo Fabiano de Franco, Paulo J. F. Tucci   +2 more
doaj   +1 more source

Electrical Storms in Brugada Syndrome: Review of Pharmacologic and Ablative Therapeutic Options [PDF]

, 2005
Electrical storm occurring in a patient with the Brugada syndrome is an exceptional but malignant and potentially lethal event. Efficient therapeutic solutions should be known and urgently applied because of the inability of usual antiarrhythmic means in
Haïssaguerre, M, Hocini, M, Maury, P
core   +2 more sources

Mortality risk stratification for Takotsubo syndrome: Evaluating CRP measurement alongside the InterTAK prognostic score

ESC Heart Failure, Volume 12, Issue 2, Page 1427-1436, April 2025.
Abstract Background and objectives Initially described as a benign acute cardiomyopathy, Takotsubo syndrome has been linked to elevated mortality rates. Emerging evidence suggests that unresolved myocardial inflammation may contribute to this adverse prognosis.
Loïc Faucher, Kensuke Matsushita, Shinnosuke Kikuchi, Taraneh Tatarcheh, Benjamin Marchandot, Amandine Granier, Said Amissi, Antonin Trimaille, Laurence Jesel, Patrick Ohlmann, Kiyoshi Hibi, Valérie Schini‐Kerth, Olivier Morel   +12 more
wiley   +1 more source

In Vitro Assessment of Drug‐Induced Liver Injury Using Three‐Dimensional Cultured HepaSH Cells Derived From Chimeric Mouse Model With Humanized Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Drug‐induced liver injury (DILI) is a serious adverse event and a common cause of postmarketing drug withdrawal. Despite nonclinical assessments of DILI risk, which are predominantly conducted in experimental animals, DILI remains a frequent adverse event, highlighting the need to improve nonclinical assessments.
Xingming Liu, Yuichiro Higuchi, Yuta Sakamoto, Shota Yanagida, Shotaro Uehara, Hiroshi Suemizu, Yasunari Kanda, Hiroyuki Kawagishi   +7 more
wiley   +1 more source

Exercise Mediated Nrf2 Signaling Protects the Myocardium From Isoproterenol-Induced Pathological Remodeling

Frontiers in Cardiovascular Medicine, 2019
Although exercise derived activation of Nrf2 signaling augments myocardial antioxidant signaling, the molecular mechanisms underlying the benefits of moderate exercise training (MET) in the heart remain elusive.
Gobinath Shanmugam, Anil K. Challa, Asokan Devarajan, Baskaran Athmanathan, Silvio H. Litovsky, Prasanna Krishnamurthy, Christopher J. Davidson, Namakkal Soorappan Rajasekaran, Namakkal Soorappan Rajasekaran, Namakkal Soorappan Rajasekaran   +9 more
doaj   +1 more source

Aqueous extract of Saussurea lappa root ameliorate oxidative myocardial injury induced by isoproterenol in rats

Journal of Advanced Pharmaceutical Technology & Research, 2013
Saussurea lappa Clarke (Compositae), is commonly known as Kushta. In Ayurvedha, it is mentioned that the aqueous extract of the root S. lappa was used for treatment of angina pectoris.
TS Mohamed Saleem, N. K. Lokanath, A. Prasanthi, M. Madhavi, G. Mallika, MN Vishnu   +5 more
semanticscholar   +1 more source

Uso de dobutamina para la inducción de arritmias durante estimulación eléctrica programada del corazón Dobutamine use for arrythmia induction during electrical programmed heart stimulation

Revista Colombiana de Cardiología, 2006
Introducción: el isoproterenol es el fármaco que se ha empleado tradicionalmente para incrementar la inducción de arritmias cuando durante la estimulación eléctrica programada del corazón en condiciones basales, no se logra su inducción. La dobutamina es
Diego I Vanegas, Climaco de J Pérez, Juan de J Montenegro, Alejandro Orjuela   +3 more
doaj  

Ginsenoside Rg2 alleviates myocardial fibrosis by regulating TGF-β1/Smad signalling pathway

Pharmaceutical Biology, 2021
Context Panax ginseng C.A. Meyer (Araliaceae) has cardioprotective effects. Ginsenosides are responsible for most of the pharmacological activities of ginseng.
Quanwei Wang, Wenwen Fu, Xiaofeng Yu, Huali Xu, Dayun Sui, Yeling Wang   +5 more
doaj   +1 more source

ADENYLYL CYCLASE TYPE 9: REGULATION AND CARDIAC FUNCTION [PDF]

, 2018
Abnormalities in cardiac stress signaling underlie a number of cardiovascular diseases (e.g. arrhythmias and heart failure). Cardiac stress signaling pathways normally integrate signals from the sympathetic nervous system to promote efficient contraction
Baldwin, Tanya A., Baldwin, Tanya A.
core   +1 more source

The Zebrafish (Danio rerio) Is a Relevant Model for Studying Sex-Specific Effects of 17β-Estradiol in the Adult Heart [PDF]

, 2019
Cardiovascular diseases are a major cause of morbidity and mortality, and there are significant sex differences therein. However, the underlying mechanisms are poorly understood.
Hassel, David, Hein, Selina, Kararigas, Georgios   +2 more
core   +1 more source