Results 61 to 70 of about 29,409 (201)

Morphological alterations in salivary glands of mice (Mus musculus) submitted to tannin enriched diets: comparison with sialotrophic effects of sympathetic agonists stimulation

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2010
In order to study the effects of tannins at histomorphological level, mice were either fed with three structurally different types of tannins (tannic acid, chestnut, and quebracho) or treated with isoproterenol, during 10 days.
E. Lamy, E.S. Baptista, A.V. Coelho, F. Capela e Silva   +3 more
doaj   +1 more source

Mechanistic insights into sex differences in atrial electrophysiology and arrhythmia vulnerability through sex‐specific computational models

The Journal of Physiology, EarlyView.
Abstract figure legend Sex‐specific models of the human atrial myocyte in normal sinus rhythm (nSR) and chronic atrial fibrillation (cAF) revealed increased alternans susceptibility in cAF males and DADs in females, driven primarily by ICaL and ryanodine receptor remodelling.
Nathaniel T. Herrera, Haibo Ni, Charlotte E. R. Smith, Yixuan Wu, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +6 more
wiley   +1 more source

Mapping DNA methylation to cardiac pathologies induced by beta-adrenergic stimulation in a large panel of mice

Epigenetics
Heart failure (HF) is a major global health challenge, contributing to over 18 million deaths annually. While the roles of genetic and environmental factors are widely studied, the role of DNA methylation in HF pathogenesis is not fully understood.
Caitlin Lahue, Eleanor Wong, Aryan Dalal, Wilson Tan Lek Wen, Shuxun Ren, Roger Foo, Yibin Wang, Christoph D. Rau   +7 more
doaj   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Senescence-like Phenotype After Chronic Exposure to Isoproterenol in Primary Quiescent Immune Cells

Biomolecules
Chronic stress is associated with a higher risk for carcinogenesis as well as age-related diseases and immune dysfunction. There is evidence showing that psychological stress can contribute to premature immunosenescence.
Michael Laumann, Philipp Palombo, Judy Fieres, Mara Thomas, Gabriele Saretzki, Alexander Bürkle, Maria Moreno-Villanueva   +6 more
doaj   +1 more source

Agonist‐specific conformational dynamics at the β2‐adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation

British Journal of Pharmacology, Volume 183, Issue 17, Page 5315-5335, September 2026.
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah, Joshua Richard, Suvankar Ghosh, Jillian Jerwick, Joice T. Gavali, Raymond B. Penn, Alexander D. MacKerell Jr, Deepak A. Deshpande   +7 more
wiley   +1 more source

Synergistic Effects of Cinnamomum verum and Stingless Bee Honey on Isoproterenol-induced Cardiac Hypertrophic Murine Model

World Journal of Traditional Chinese Medicine
Objective: This study aimed to validate the synergistic effects of Cinnamomum verum (C. verum) barks and stingless bee honey (SBH) against cardiac hypertrophy (CH). Materials and Methods: Isoproterenol (ISO-group II-30 mg/kg)-induced cardiac hypertrophic
Arul Mozhi Padmanabhan, Victor Arokia Doss   +1 more
doaj   +1 more source

Heart‐Specific Spinal and Vagal Afferents: Transcriptomic Signatures and Optogenetically Modulated Functional Coupling With Cardiomyocytes

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Selective purification of heart‐specific spinal and vagal sensory neurons by retrograde labeling and FACS purification showed enhanced spontaneous, optogenetic, and chemically stimulated Ca2+ activity. Transcriptomic profiling identified distinct ion channel and GPCR signatures in heart‐specific sensory neurons.
T. Akgul Caglar, Y. E. Kazci, Z. B. Durdu, S. Sahoglu Goktas, S. Bay, E. Vatandaslar, M. U. Turhan, G. Ozturk, E. Cagavi   +8 more
wiley   +1 more source

Na+,-K+-ATPase Deficiency Exacerbates Cardiac Fibrosis via Promoting ERRα-Mediated Myocardial Cell Injury and Macrophage Activation Under Isoproterenol-Challenged Conditions

Frontiers in Bioscience-Landmark
Background: Inflammation plays a pivotal role in the progression of tissue fibrosis. Our previous research demonstrated that Na+, K+-ATPase (NKA) α1 deficiency impairs mitochondrial function and accelerates isoproterenol (ISO)-induced ...
Ting Lei, Tao Liu, Yutong Liu, Yingnan Zhai, Ruijia Wang, Xiaoyi Tan, Hongli Liu, Xiaofei Yan   +7 more
doaj   +1 more source

Postoperative Nausea and Vomiting After Deep Sedation for Radiofrequency Catheter Ablation in Pediatric Patients

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
This retrospective study investigated the incidence of postoperative nausea and vomiting (PONV) in 70 pediatric radiofrequency catheter ablation procedures under deep sedation. PONV occurred in 17% of procedures, with a significantly higher incidence following left‐sided ablation. Importantly, the majority of PONV symptoms resolved spontaneously within
Yoshikatsu Takeda, Shuhei Fujita, Naoto Sakumura, Kazuyuki Ueno, Kengo Miyashita, Takeshi Futatani, Akio Chikata, Kazuo Usuda, Hidenori Iwasaki, Taichi Nakamura, Kunio Ohta, Taizo Wada   +11 more
wiley   +1 more source