Results 51 to 60 of about 29,409 (201)

Time-dependent responses of rat troponin I and cardiac injury following isoproterenol administration [PDF]

Medicinski Glasnik, 2011
Aim To develop a rat model of myocardial infarction induced by isoproterenol (ISO). We investigated a type of histological myocardial changes and cardiac troponin I (TnI) kinetic. Methods The study has used adult, male, Wistar strain rats.
Sabaheta Hasić, Radivoj Jadrić, Emina Kiseljaković, Amina Valjevac, Zakira Mornjaković, Mira Winterhalter-Jadrić   +5 more
doaj  

The V6R/V4R Index: A Novel ECG Parameter for Identifying Idiopathic Ventricular Arrhythmias Originating From the Aortic Cusp

Journal of Cardiovascular Electrophysiology, EarlyView.
The V6R/V4R amplitude index is a novel and practical electrocardiographic parameter for identifying idiopathic ventricular arrhythmias originating from the aortic cusp. A cutoff >0.55 accurately distinguishes cusp from adjacent non‐cusp origins within the left ventricular outflow tract, facilitating targeted mapping and procedural planning.
Yoshihisa Naruse, Kohki Nakamura, Kanae Hasegawa, Toshihiko Tsuji, Machiko Miyoshi, Tatsuhiro Kataoka, Hideyuki Aoki, Yoshinori Okazaki, Shigeto Naito, Hiroshi Tada, and other members of the V6R/V4R Study Group, Tomoki Kaeriyama, Shigeki Horiguchi, Kaori Hisazaki, Takehito Sasaki, Kentaro Minami, Yutaro Kaneko, Taro Narumi, Makoto Sano, Yuichiro Maekawa   +19 more
wiley   +1 more source

Alchemilla vulgaris modulates isoproterenol-induced cardiotoxicity: interplay of oxidative stress, inflammation, autophagy, and apoptosis

Frontiers in Pharmacology
Introduction: Isoproterenol (ISO) is regarded as an adrenergic non-selective β agonist. It regulates myocardial contractility and may cause damage to cardiac tissues.
Nuha Anajirih, Ahmed Abdeen, Ehab S. Taher, Afaf Abdelkader, Hoda A. Abd-Ellatieff, Mahmoud S. Gewaily, Nashwa E. Ahmed, Rasha H. Al-Serwi, Safwa M. Sorour, Heba M. Abdelkareem, Heba M. Abdelkareem, Elturabi Ebrahim, Mohamed El-Sherbiny, Florin Imbrea, Ilinca Imbrea, Mahmoud M. Ramadan, Mahmoud M. Ramadan, Ola A. Habotta   +17 more
doaj   +1 more source

Dynamic Behavior of Left Atrial Low‐Voltage Areas in Persistent Atrial Fibrillation: Implications for Substrate‐Guided Ablation

Journal of Cardiovascular Electrophysiology, EarlyView.
Patient selection and analysis flow diagram. The exact pre‐inclusion denominator and reliable reason‐specific exclusion counts could not be reconstructed because a prospectively maintained screening log was unavailable. The diagram summarizes the final study cohort and analysis‐specific sample sizes. AF, atrial fibrillation; LVA, low‐voltage area; SR1,
Yunus Emre Özbebek, Özcan Özdemir, Sinan Boz, Haluk Furkan Şahan, Engin Algül, Sinan İşcen, Hamza Sunman, Tolga Han Efe   +7 more
wiley   +1 more source

Betulin protects against isoproterenol-induced myocardial injury by inhibiting NF-κB signaling and attenuating cardiac inflammation and oxidative stress in rats

Asian Pacific Journal of Tropical Biomedicine
Objective: To investigate the cardioprotective potential of betulin in isoproterenol (ISO)-induced myocardial injury in rats. Methods: Wistar rats were divided into five groups (n=10): normal, ISO, nebivolol 5 mg/kg, and betulin (20 & 40 mg/kg ...
Hital Shah, Tejal Gandhi
doaj   +1 more source

Intravenous delivery of a microRNA-1 agomir improves isoproterenol-induced heart failure in mice

Di-san junyi daxue xuebao, 2019
Objective To investigate the therapeutic effect of intravenous administration of a microRNA-1 (miR-1) agomir on isoproterenol (ISO)-induced heart failure (HF) in mice. Methods Mouse models of HF were established by intraperitoneal injection of ISO for 28
HE Rui, DING Chang, HE Li
doaj   +1 more source

Arctic lake trout (Salvelinus namaycush) show evidence of seasonal acclimation of cardiac adrenergic sensitivity but not heat tolerance

Journal of Fish Biology, EarlyView.
Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams, Les N. Harris, Jean‐Sébastien Moore, Ella K. Middleton, Shira A. Berkelhammer, Ben Speers‐Roesch, Matthew J. H. Gilbert   +6 more
wiley   +1 more source

Ficus carica leaf extract ameliorates cardiac injury through Nrf2/Keap1 pathway activation and dual oxidase inhibition [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): To investigate the therapeutic potential of Ficus carica leaf extract (FCLE) against high-fat diet (HFD) coupled with isoproterenol-induced cardiac injury in a rat model that mimics myocardial infarction.Materials and Methods: HPLC was ...
Najeeb Ullah Khan, Shamshad Ul Hassan, Bilal Aslam, Saqib Umer   +3 more
doaj   +1 more source

Sex‐specific differences in mortality and neurocardiac interactions in the Kv1.1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP)

The Journal of Physiology, EarlyView.
Abstract figure legend The Kcna1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP) exhibits sex‐specific differences in SUDEP risk. Female mice exhibit a lower SUDEP risk than males, despite similar seizure characteristics and interictal cardiac function across sexes.
Kelsey Paulhus, Praveen Kumar, Kelly Kneale, T. Noah Hutson, Nicole M. Gautier‐Hall, Deng‐Shan Shiau, Megan Watts, Krystle Trosclair, Hemangini A. Dhaibar, Paari Dominic, Leonidas Iasemidis, Edward Glasscock   +11 more
wiley   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source