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Asymmetric Synthesis of Isoquinoline Alkaloids
Chemical Reviews, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
Maria Chrzanowska, Maria D. Rozwadowska
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Cyanochlorination and cyanogenation of isoquinoline
Journal of the Chemical Society D: Chemical Communications, 1969Isoquinoline reacts with potassium cyanide and sulphuryl chloride to give, depending upon the reaction conditions, 4-chloro-1-cyano-, 1,3-dicyano-, 1-aminocarbonyl-3-cyano-, 3-cyano-, and 1-cyano-isoquinoline, thus illustrating a simple method for the direct introduction of chloro- and cyano-substituents into nitrogen heterocycles.
S. L. Tan, B. C. Uff, G. W. Kirby
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Isoquinolines as receptors for resorcinol
Tetrahedron Letters, 1994Abstract Multiple condensation reactions based on the Pictet-Gams isoquinoline synthesis lead to receptors for resorcinol. The host-guest interaction is confirmed by anisotropic highfield shifts and by NOE enhancement between aryl protons.
Gerald Dyker+3 more
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ChemInform, 1996
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Qun Sun, Edmond J. LaVoie
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AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Qun Sun, Edmond J. LaVoie
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Cyanochlorination and cyanation of isoquinolines
Journal of the Chemical Society, Perkin Transactions 1, 1979Treatment of isoquinoline with sulphuryl chloride and potassium cyanide gave, in one preparative step, 4-chloro-1-cyanoisoquinoline and 1-carbamoyl-3-cyanoisoquinoline in yields dependent upon the proportions of reagents. 4-Chloroisoquinoline, 1,3-dicyanoisoquinoline, 3-cyanoisoquinoline, and 1-cyanoisoquinoline were also produced under different ...
Seng Leong Tan+2 more
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The reductive alkylation of isoquinoline
Journal of the Chemical Society C: Organic, 1966Reductive alkylation of isoquinoline with benzaldehyde in acetic acid gives a mixture of 2-benzyl-, 4-benzyl-, and 2,4-dibenzyl-1,2,3,4-tetrahydroisoquinolines and 4-benzylisoquinoline. Contrary to earlier reports, the major product is 2-benzyl-1,2,3,4-tetrahydroisoquinoline, not the 4-isomer.
P. Garside, A. C. Ritchie
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Pictet–Gams isoquinoline synthesis
2002The isoquinoline framework is derived from the corresponding acyl derivatives of β-hydroxy-β-phenylethylamines. Upon exposure to a dehydrating agent such as phosphorus pentoxide, or phosphorus oxychloride, under reflux and in an inert solvent such as decalin, isoquinoline frameworks are formed.
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Isoquinoline and its derivatives
1991Publisher Summary This chapter covers the chemistry on isoquinoline for the period of 10 years (1985 to 1995). Excellent reviews are published for isoquinoline chemistry, the structure, reactivity, and synthesis of some isoquinolines and hydroisoquinolines that have been reviewed under pyridines and their benzo derivatives in a more concise form in ...
Marudai Balasubramanian+1 more
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The Biosynthesis of Isoquinoline Alkaloids
1985The tetrahydroisoquinoline skeleton occurs in numerous plant alkaloids. The simplest bearers of this structural unit are exemplified by anhalonidine (12) (Sect. 2). Slightly more elaborate are the benzylisoquinoline alkaloids exemplified at their simplest by reticuline (25) and papaverine (27) (Sect. 3).
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Some Substituted Isoquinolines
Journal of the American Chemical Society, 1947Henry Gilman, Gordon C. Gainer
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