Results 241 to 250 of about 29,358 (323)

Nitration of Pyrrolo[2,1-a]isoquinolines.

Journal of Organic Chemistry, 2023
We have successfully modified a series of pyrrolo[2,1-a]isoquinolines via direct nitration under mild reaction conditions. Easily accessible nitrates including CAN, Cu(NO3)2·H2O, and Fe(NO3)3·9H2O all can serve as effective nitrating reagents for ...
Xiao-Hui Chen, Danyang Ma, Xin Gao, Yun-Meng Li, Da-Bo Jiang, Chao Ma, H. Cui   +6 more
semanticscholar   +1 more source

Synthesis of Ester-Substituted Indolo[2,1-a]isoquinolines via Photocatalyzed Alkoxycarbonylation/Cyclization Reactions.

Organic Letters, 2022
A direct alkoxycarbonylation/cyclization reaction is accomplished under visible light-induced photoredox catalysis. With this approach, a variety of ester-substituted indolo[2,1-a]isoquinolines are prepared in good to excellent yields. It is worth noting
Jian-Qiang Chen, Xi-Feng Tu, Binyan Qin, Shaoxin Huang, Jun Zhang, Jie Wu   +5 more
semanticscholar   +1 more source

Pyridine Derivatives as Insecticides. Part 3. Synthesis, Crystal Structure, and Toxicological Evaluation of Some New Partially Hydrogenated Isoquinolines against Aphis gossypii (Glover, 1887).

Journal of Agricultural and Food Chemistry, 2022
Three new series of isoquinolines, that is, 7-acetyl-3-acetonylsulfanyl-8-aryl-1,6-dimethyl-6-hydroxy-5,6,7,8-tetrahydroisoquinoline-4-carbonitriles (3a-c); 3-acetonylsulfanyl-8-aryl-1,6-dimethyl-7,8-dihydroisoquinoline-4-carbonitriles (4a-c); and 7 ...
E. A. Bakhite, I. S. Marae, M. Gad, S. Mohamed, J. Mague, Suzan Abuelhassan   +5 more
semanticscholar   +1 more source

Rh(III)-Catalyzed Defluorinative [4 + 2] Annulation of N-Sulfonylarylamides with Ethyl 2-Diazo-3,3,3-trifluoropropanoate: Synthesis of 1,3,4-Functionalized Isoquinolines.

Organic Letters, 2022
Using 2-diazo-3,3,3-trifluoropropanoate as a nontraditional two-carbon reaction partner, a Rh(III)-catalyzed defluorinative [4 + 2] annulation for the synthesis of 1,3,4-functionalized isoquinolines was developed.
Hao-Xiang Li, M. Mei, Lei Zhou
semanticscholar   +1 more source

Super-Electron-Donor 2-Azaallyl Anions Enable Construction of Isoquinolines.

Organic Letters, 2022
Herein is introduced the application of "super-electron-donor"(SED) 2-azaallyl anions in a tandem reduction/radical cyclization/radical coupling/aromatization protocol that enables the rapid construction of isoquinolines.
Quanxing Zi, Minyan Li, Jielun Cong, Guogang Deng, Shengzu Duan, Meng Yin, Wen Chen, Hong Jing, Xiaodong Yang, P. Walsh   +9 more
semanticscholar   +1 more source

Copper-Catalyzed Construction of Benzo[4,5]imidazo[2,1-a]isoquinolines Using Calcium Carbide as a Solid Alkyne Source.

Organic Letters, 2021
A method for the synthesis of benzo[4,5]imidazo[2,1-a]isoquinolines through Sonogashira cross-coupling/nucleophilic addition tandem reactions using calcium carbide as a solid alkyne source, 2-(2-bromophenyl)benzimidazoles as starting materials, and ...
Haiyan Liu, Zheng Li
semanticscholar   +1 more source

Microwave-Assisted Palladium-Catalyzed Reductive Cyclization/Ring-Opening/Aromatization Cascade of Oxazolidines to Isoquinolines.

Organic Letters, 2021
An efficient palladium-catalyzed reaction of N-propargyl oxazolidines for the construction of 4-substituted isoquinolines under microwave irradiation is developed.
Xianjun Xu, H. Feng, E. V. Van der Eycken   +2 more
semanticscholar   +1 more source

One-Pot Synthesis of Furo[3,4-c]indolo[2,1-a]isoquinolines through Rh(III)-Catalyzed Cascade Reactions of 2-Phenylindoles with 4-Hydroxy-2-alkynoates.

Organic Letters, 2020
An efficient and regioselective synthesis of fused polycyclic furo[3,4-c]indolo[2,1-a]isoquinolines through Rh(III)-catalyzed cascade C-H activation/annulation/lactonization of 2-arylindoles and 4-hydroxy-2-alkynoates has been developed.
Yihao Liu, Zi Yang, R. Chauvin, W. Fu, Zhenyu Yao, Lianhui Wang, Xiuling Cui   +6 more
semanticscholar   +1 more source

Visible-light-driven Difluoromethylation of Isocyanides with S-(Difluoromethyl)diarylsulfonium Salt: Access to a Wide Variety of Difluoromethylated Phenanthridines and Isoquinolines.

Journal of Organic Chemistry, 2020
A highly efficient approach of visible-light-driven radical difluoromethylation of isocyanides to access a wide variety of difluoromethylated phenanthridines and isoquinolines was herein described.
Wenbing Qin, Wei Xiong, Xin Li, Jiayi Chen, Li-Ting Lin, H. Wong, Guokai Liu   +6 more
semanticscholar   +1 more source

Hydrodenitrogenation of isoquinoline

Applied Catalysis A: General, 1999
Abstract To determine the formation and reactivity of addition compounds produced during hydrodenitrogenation (HDN), we investigated the HDN of isoquinoline for a sulfided Ni–Mo/Al 2 O 3 catalyst operated under a hydrogen pressure of 12 MPa (cold charge) in the temperature range 300–375°C.
Yoshikazu Sugimoto, Yasuo Miki
openaire   +2 more sources