Results 251 to 260 of about 15,657 (274)
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Isoquinolines in Parkinson’s Disease
20001,2,3,4-Tetrahydroisoquinoline (TIQ) derivatives, which chemically resemble MPTP, exist in mammals and have been proposed as candidates for endogenous parkinsonogenic compounds. TIQ, l-benzyl-l,2,3,4-tetrahydroisoquinoline (1-benzyl-TIQ) could induce parkinsonism in rodents and a primate.
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CXXII.—isoQuinoline and the isoquinoline-reds
J. Chem. Soc., Trans., 1922William Jackson Pope +1 more
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2015
This chapter reviews a non-exhaustive number of close to 200 natural products and lead compounds with isoquinoline scaffolds used in drug development. Two classes of small-molecule drug candidates are discussed: firstly, those derived from natural products and, secondly, those that are chemically engineered based on structure–activity relationships ...
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This chapter reviews a non-exhaustive number of close to 200 natural products and lead compounds with isoquinoline scaffolds used in drug development. Two classes of small-molecule drug candidates are discussed: firstly, those derived from natural products and, secondly, those that are chemically engineered based on structure–activity relationships ...
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Isoquinoline Alkaloids and Chemotaxonomy
2019The isoquinoline alkaloids are a class of secondary metabolites classified into different groups, being the aporphinoids the most representative class. They are considered the second-largest class of alkaloids in terms of structural diversity staying behind only of indole alkaloids.
Nelissa P. Vaz +1 more
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Arsenicals in the Isoquinoline Series
Journal of the American Chemical Society, 1946Cliff S. Hamilton, Bill Elpern
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A new approach to isoquinolines
Tetrahedron Letters, 1968Robert A. Arnold +3 more
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Isoquinolines. 2. 3-(Dialkylaminoalkylamino)isoquinolines as potential antimalarial drugs
Journal of Medicinal Chemistry, 1970Neumeuer Jl, Weinhardt Kk
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ChemInform Abstract: Simple Isoquinoline Alkaloids
ChemInform, 1986Gregory L. Lavanier +4 more
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