Results 121 to 130 of about 83,055,373 (182)

Rechallenge With Cisplatin After an Acute Coronary Event. [PDF]

open access: yesJACC Case Rep
Jaffery Z   +3 more
europepmc   +1 more source

Associations of Brain Morphology and Cognitive Function With Ambulatory Estimated Pulse Wave Velocity. [PDF]

open access: yesJ Am Heart Assoc
Cheng YB   +7 more
europepmc   +1 more source
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Isosorbide 5-Mononitrate Pharmacokinetics in Humans

Biopharmaceutics and Drug Disposition, 1981
AbstractWhen isosorbide 5‐mononitrate was intravenously infused at a rate of 4 mg h −1 for 2.5 h to five human subjects, its concentrations in plasma increased slowly to 185 ng ml−1 ± 5 per cent C.V. at 2.5 h and a steady‐state plasma level was not reached during the infusion. When the infusion was discontinued, plasma drug concentrations declined with
E Doyle, L F Chasseaud, A Darragh
exaly   +3 more sources

Isosorbide-5-mononitrate versus propranolol in the prevention of first bleeding in cirrhosis

open access: yesGastroenterology, 1993
Hemodynamic studies have shown the efficacy of nitrates in reducing portal pressure in cirrhosis. We therefore studied the efficacy of isosorbide-5-mononitrate vs. propranolol in the prevention of first bleeding within a prospective controlled trial.One hundred eighteen cirrhotics with esophageal varices were blindly randomized to receive 20 mg of ...
ANGELICO, MARIO   +6 more
core   +5 more sources

Improved Extraction Procedure for the Assay of Isosorbide-5-Mononitrate in Serum

Journal of Chromatography B, Biomedical Sciences and Applications, 1996
A procedure is described for the extraction of isosorbide-5-mononitrate from serum with diethyl ether-n-butyl acetate (15:1, v/v). After extraction, the diethyl ether is evaporated at room temperature and the nitrate remains dissolved in the relatively non-volatile n-butyl acetate phase. Glassware must be used throughout as the recovery of isosorbide-5-
J M, Pennings, J M, de Haas
exaly   +3 more sources

Isosorbide 5-mononitrate kinetics

Clinical Pharmacology and Therapeutics, 1984
The kinetics of isosorbide 5-mononitrate (5-ISMN) were studied in 12 healthy subjects after intravenous infusion and oral doses of 20 mg. Kinetic parameters calculated by model-independent methods or by assumption of a one-compartment open model were in good agreement.
R M, Major   +4 more
openaire   +2 more sources

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