Results 71 to 80 of about 8,875 (220)

Dinitrato de isosorbide sublingual en la urgencia hipertensiva

open access: yesRevista Cubana de Medicina, 1998
Se investigó el uso del dinitrato de isosorbide sublingual en la urgencia hipertensiva. Se estableció además una correlación con la nifedipina, de eficacia probada para este fin.
Haydeé Aurora del Pozo Jerez   +3 more
doaj  

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1463-1476, December 2025.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu   +21 more
wiley   +1 more source

Improving Postdischarge Outcomes in Acute Heart Failure [PDF]

open access: yes, 2018
The global burden that acute heart failure (AHF) carries has remained unchanged over the past several decades (1). European registries (2–5) showed that 1-year outcome rates remain unacceptably high (Table 1) and confirm that hospitalization for AHF ...
Ambrosy, Andrew P.   +8 more
core   +1 more source

Clinical Pharmacogenetics Implementation Consortium Guideline for NAT2 Genotype and Hydralazine Therapy

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1430-1436, December 2025.
Hydralazine is a vasodilator typically used in the treatment of resistant hypertension and heart failure. N‐acetyltransferase 2 (NAT2) catalyzes the metabolism of hydralazine into inactive metabolites. NAT2 poor metabolizers (historically referred to as “slow acetylators”) are predicted to have increased plasma hydralazine concentrations compared with ...
Michael T. Eadon   +18 more
wiley   +1 more source

Optimized antianginal therapy: a randomized, comparative study of long-acting isosorbide-5-mononitrate and isosorbide dinitrate in patients with coronary heart disease and stable effort angina

open access: yesКардиоваскулярная терапия и профилактика, 2005
Aim. To compare effectiveness and tolerability of a regular treatment with two nitrates – moderately long-acting isosorbide dinitrate and very long-acting isosorbide-5-mononitrate – in patients with coronary heart disease (CHD) and stable effort angina ...
Yu. E. Semenova   +6 more
doaj  

PCV51 POSSIBILITIES OF NEW TECHNOLOGIES AMONG PATIENTS WITH HYPERTENSION: FEASIBILITY AND ACCEPTANCE OF AN EDUCATIVE INTERVENTION THROUGH SHORT MESSAGES TO THE PATIENT'S CELLULAR PHONE [PDF]

open access: yes, 2002
The patterns of innovation diffusion are well approximated by the logistic curves. This is the robust empirical fact confirmed by many studies in innovations dynamics.
De la Figuera, M   +6 more
core   +1 more source

Pharmacologic pitfalls in heart failure: A guide to drugs that may cause or exacerbate heart failure. A European Journal of Heart Failure expert consensus document

open access: yesEuropean Journal of Heart Failure, Volume 27, Issue 12, Page 2671-2690, December 2025.
Main categories of harmful drugs in heart failure. CCB, calcium channel blocker; DPP4i, dipeptidyl peptidase‐4 inhibitor; HER2‐TT, human epidermal growth factor receptor 2‐targeted therapy; NSAID, non‐steroidal anti‐inflammatory drug; TKI, tyrosine kinase inhibitor; TZD, thiazolidinedione; VEGF Inh, vascular endothelial growth factor inhibitor.
Amr Abdin   +16 more
wiley   +1 more source

Influence of Sacubitril/Valsartan (LCZ696) on 30-day readmission after heart failure hospitalization [PDF]

open access: yes, 2016
Background: Patients with heart failure (HF) are at high risk for hospital readmission in the first 30 days following HF hospitalization. Objectives: This study sought to determine if treatment with sacubitril/valsartan (LCZ696) reduces rates ...
Claggett, Brian L.   +11 more
core   +2 more sources

Analysis of outcomes in patients with HeartMate 3 with and without right ventricular assist device support

open access: yesESC Heart Failure, Volume 12, Issue 5, Page 3306-3319, October 2025.
Temporary RVAD support following HM3 LVAD is associated with high morbidity and mortality. Temporary RVAD support occurs most frequently in INTERMACS 1 or 2 patients and those who require pre‐operative VA‐ECMO. In addition to higher post‐operative mortality, a significantly higher risk of both dialysis and stroke at 1 year post‐implant was observed in ...
Vinh Q. Chau   +12 more
wiley   +1 more source

COMPARATIVE ASSESSMENT OF LARGE ARTERY ELASTICITY IN PATIENTS WITH STABLE ANGINA RECEIVING METABOLIC THERAPY

open access: yesРоссийский кардиологический журнал, 2012
Aim. To assess the effects of metabolic therapy, administered together with standard antianginal treatment, on large artery elasticity and endotheliumdependent vasodilation in patients with stable angina and subsequent heart failure. Material and methods.
O. V. Ilukhin   +5 more
doaj  

Home - About - Disclaimer - Privacy