Results 1 to 10 of about 2,809 (154)

Synergetic delivery of artesunate and isosorbide 5-mononitrate with reduction-sensitive polymer nanoparticles for ovarian cancer chemotherapy [PDF]

Journal of Nanobiotechnology, 2022
Ovarian cancer is a highly fatal gynecologic malignancy worldwide. Chemotherapy remains the primary modality both for primary and maintenance treatments of ovarian cancer. However, the progress in developing chemotherapeutic agents for ovarian cancer has
Guang Li, Mingjian Ling, Kunyi Yu, Wei Yang, Qiwen Liu, Lijuan He, Xuzi Cai, Min Zhong, Ziyi Mai, Rui Sun, Yuanling Xiao, Zhiqiang Yu, Xuefeng Wang   +12 more
doaj   +2 more sources

Evaluation of isosorbide-5-mononitrate as a cervical ripening agent prior to induced abortion in contrast to misoprostol- a randomized controlled trial [PDF]

Obstetrics & Gynecology Science, 2019
ObjectiveTo determine whether vaginal application of 40 mg isosorbide-5-mononitrate (ISMN) has a comparable cervical ripening efficacy to and lesser side effects than 400 µg misoprostol in women scheduled for the first trimester induced abortion using a ...
Aloke Kumar De, Bhattacharyya Sanjoy Kumar, Aparna Chakraborty, Amrita Samanta   +3 more
doaj   +2 more sources

Determination of Isosorbide-5-Mononitrate in Human Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry and Its Application to a Bioequivalence Study [PDF]

Journal of Analytical Methods in Chemistry, 2020
Isosorbide-5-mononitrate (5-ISMN), an organic nitrate vasodilator, has been widely used worldwide to prevent angina pectoris for more than two decades.
Yinping Zhou, Aijing Liu, Ranran Jia, Mengyi Wu, Ni Wu, Chunyan Liu, Zhihui Han, Haitang Hu, Hongyun Wang, Qing He   +9 more
doaj   +2 more sources

Pharmacokinetics and Safety with Bioequivalence of Isosorbide Mononitrate Sustained-Release Tablets in Chinese Healthy Volunteers: Bioequivalence Study [PDF]

Drug Design, Development and Therapy
Binbin Wu,1 Wei Wang,2 Qikun Zhang,3 Guigui Yu,1 Jingjing Lin,1 Ting Zhang,1 Luxi Ye,1 Keli Wang,4 Wanggang Zhang,5,* Xinyi Wu5,* 1Department of Nephrology, Zhejiang Hospital, Hangzhou, 310030, People’s Republic of China; 2Department of ...
Wu B, Wang W, Zhang Q, Yu G, Lin J, Zhang T, Ye L, Wang K, Zhang W, Wu X   +9 more
doaj   +2 more sources

Comparison of Topical Isosorbide Mononitrate, Topical Diltiazem, and Their Combination in the Treatment of Chronic Anal Fissure

Asian Journal of Surgery, 2013
Background/Objective: Chronic anal fissure is a painful condition that is associated with an increase in internal anal sphincter pressure. The main aim of this study is to evaluate the efficacy and adverse effects of topical isosorbide 5 mononitrate and ...
Adnan Tas
exaly   +3 more sources

Comparative cardioprotective effects of Kuanxiong Aerosol and its individual components in a rat model of acute myocardial infarction [PDF]

Pharmaceutical Biology
Context Kuanxiong Aerosol (KXA), composed of volatile oils from sandalwood (Santalum album L.), galangal (Alpiniae Officinarum Rhizoma), asarum (Asari Radix), pepper (Piper longum L.), and borneol, is used to treat cardiovascular conditions. However, its
Kai Qian, Xiao-jing Fan, Xiao-kang Peng, Ye-feng Chen, Meng-meng Xu, Jin-ting Zhang, Yang-yang Zhu, Tao Yang, Yuan-hang Zheng, Yu Tang, Yi Luo   +10 more
doaj   +2 more sources

Second trimester a abortion induction with misoprostol only versus misoprostol plus isosorbide mononitrate: a randomized controlled study [PDF]

Al-Azhar International Medical Journal, 2022
Background: Efficacy of isosorbide mononitrate to reduce the interval of induction time in second trimester missed abortion . Aim of the study: To compare efficacy and safety of Isosorbide Mononitrate (IMN) and misoprostol for cervical ripening in ...
Emad Atalla
doaj   +1 more source

Vericiguat in combination with isosorbide mononitrate in patients with chronic coronary syndromes: The randomized, phase Ib, VISOR study

Clinical and Translational Science, 2022
Vericiguat was developed for the treatment of symptomatic chronic heart failure (HF) in adult patients with reduced ejection fraction who are stabilized after a recent decompensation event.
Michael Boettcher, Gerd Mikus, Dietmar Trenk, Hans‐Dirk Düngen, Frank Donath, Nikos Werner, Mahir Karakas, Nina Besche, Dominik Schulz‐Burck, Mireille Gerrits, James Hung, Corina Becker   +11 more
doaj   +1 more source

A COMPARATIVE STUDY OF EFFICACY AND TOLERABILITY OF ANTIANGINAL DRUGS OF DIFFERENT GROUPS — NITROVASODILATATOR (ISOSORBIDE-5-MONONITRATE SUSTAINED RELEASE) AND BETA-BLOCKER WITH VASODILATING ACTION (NEBIVOLOL) — IN PATIENTS WITH STABLE ANGINA

Рациональная фармакотерапия в кардиологии, 2016
Aim. To compare the efficacy and safety of the slow-release isosorbide-5-mononitrate and of the nebivolol in patients with stable angina. Material and Methods.
S. Yu. Martsevich, N. P. Kutishenko, V. A. Egorov, A. V. Zagrebel'nyy, A. A. Serazhim, Yu. V. Lukina, N. A. Dmitrieva   +6 more
doaj   +1 more source

Comparative Study Between Combined Vaginal Misoprostol With Isosorbid-5-mononitrate Versus Misoprostol Alone for Induction of Second Trimesteric Abortion [PDF]

Al-Azhar International Medical Journal
Background: For medical reasons, prostaglandins or their analogs are frequently given during second-trimester abor tions to relax the uterine cervix.
Abdel Moneim Mohamed Zakaria, Yasser Mohamed Said Diab, Elsayed Ahmed Badr Khalil   +2 more
doaj   +1 more source