Results 21 to 30 of about 83,055,373 (182)
Liposome-encapsulated ISMN: a novel nitric oxide-based therapeutic agent against Staphylococcus aureus biofilms. [PDF]
PLoS ONE, 2014 Staphylococcus aureus in its biofilm form has been associated with recalcitrant chronic rhinosinusitis with significant resistance to conventional therapies.
Camille Jardeleza +6 more
doaj +1 more source
Isosorbide-5-mononitrate and endothelial function: a wolf in sheep's clothing [PDF]
European Heart Journal, 2012 This editorial refers to ‘Chronic therapy with isosorbide-5-mononitrate causes endothelial dysfunction, oxidative stress, and a marked increase in vascular endothelin-1 expression’[†][1], by M. Oelze et al. , on page 3206 In 1846, Ascanio Sobrero first synthesized nitroglycerin and observed that a small quantity of the oily substance placed on the ...
Tienush, Rassaf, Malte, Kelm
openaire +2 more sources
Artery Research, 2009 Background: The cuff sphygmomanometer failed to show consistent alteration in brachial blood pressure with slow-release isosorbide-5-mononitrate(IS-5-MN), even though the drug proved very effective in relieving angina pectoris.Sofar, the effect of orally
Shu-xian Du +4 more
doaj +1 more source
, 1992 Isosorbide-5-mononitrate and isosorbide-2-mononitrate, the metabolites of isosorbide dinitrate, were studied for their effects on the contractile and electrical activity and on the content of cyclic nucleotides in isolated heart muscles of guinea-pig and
R Balansky +3 more
core +1 more source
Influence of emotional stress on pharmacokinetics of isosorbide dinitrate intraperitoneally administered to rats. [PDF]
, 1990 The plasma level of isosorbide dinitrate intraperitoneally administered to rats stressed by foot-shock was almost the same as that in non-stressed control rats.
Araki, Yasunori +2 more
core +1 more source
Isosorbide mononitrate inhibits myocardial fibrosis in diabetic rats by up-regulating exosomal MiR-378 [PDF]
, 2022 Purpose: To investigate the effect of isosorbide mononitrate on diabetic cardiomyopathy (DCM), and the potential mechanism of action.Methods: The effects of isosorbide mononitrate and isosorbide mononitrate + GW4869 on cardiac function and myocardial ...
Zhao, Kaidi +3 more
core +1 more source
Медицинский совет, 2019 Cardiovascular complications of type 2 diabetes mellitus (T2DM) are now a global health problem, due to their main cause of mortality of these patients. Ischemic heart disease (IHD) among all cardiovascular diseases occupies a leading position.
Zh. M. Sizova +2 more
doaj +1 more source
Saudi Pharmaceutical Journal, 2022 Background: The therapeutic activity of Glyceryl trinitrate (GTN) is mainly regulated by liberating nitric oxide (NO) and reactive nitrogen species (RNS).
Ahmed Mohsen Elsaid Hamdan +3 more
doaj +1 more source
Nitric oxide donors for treatment of isolated oligohydramnios: A randomized controlled trial
Middle East Fertility Society Journal, 2018 Objective: To evaluate the effect of vaginal isosorbide mononitrate (IMN) plus oral hydration compared with oral hydration alone in improving the amniotic fluid index (AFI) and obstetric and perinatal outcomes in pregnancies complicated by isolated ...
Ahmed Walid Anwar Morad +1 more
doaj +1 more source
, 1994 Eighteen cirrhotic patients with esophageal varices at risk for bleeding took part in a double-blind study. The variations in PFV induced by either 40 mg of propranolol or 60 mg of sustained-release isosorbide-5-mononitrate on two consecutive days were ...
A. Vignoli +8 more
core +1 more source