Results 231 to 240 of about 317,446 (301)

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

open access: yesSmart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin   +10 more
wiley   +1 more source

Tailoring Laser Powder Bed Fusion and Post‐Processing Parameters for JIS SKD61 Tool Steels: Surface Roughness, Microstructure, and Mechanical Properties

open access: yessteel research international, EarlyView.
Laser powder bed fusion of JIS SKD61 tool steel is systematically optimized using a Taguchi design and ANOVA. Hatch spacing and layer thickness are identified as dominant parameters controlling surface roughness and tensile strength. Subsequent tempering at 600°C improves microstructural stability and mechanical performance, enabling high‐density SKD61
Masrurotin Masrurotin   +4 more
wiley   +1 more source

Effect of Double Annealing on the Microstructure and Mechanical Properties of a Medium Manganese Steel

open access: yessteel research international, EarlyView.
A double intercritical annealing strategy is proposed to tailor the multiphase microstructure and mechanical response of a medium‐Mn steel. The treatment produces an ultrafine mixture of ferrite, martensite and multiple austenite populations with graded thermal and mechanical stability, formed through austenite reversion and controlled retransformation.
Mattia Franceschi   +3 more
wiley   +1 more source

Development of an isothermal point of care method for detection of human papilloma virus (HPV). [PDF]

open access: yesAsp Mol Med
Zingg JM   +5 more
europepmc   +1 more source

Substrate-Assisted Flux Method for Robust Synthesis of Quantum-Grade Transition Metal Dichalcogenides. [PDF]

open access: yesSmall Methods
Li Y   +16 more
europepmc   +1 more source

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