Results 1 to 10 of about 257,349 (337)

Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model [PDF]

, 2012
Ovarian cancer is the leading cause of cancer related deaths in women. Genetic alterations including overexpression of EGFR play a crucial role in ovarian carcinogenesis.
Joseph Alan Bauer, Parul Gupta, Prabodh K. Kandala, Sanjay K. Srivastava, Sivakumar Loganathan   +4 more
core   +13 more sources

Optimization of Germination Process of Isothiocyanate Enrichment in Broccoli Sprouts by Response Surface Methodology

Shipin gongye ke-ji, 2022
The accumulation of isothiocyanate in germinated broccoli under ZnSO4-melatonin treatment was optimized. The isothiocyanate content, bud length and fresh weight of broccoli during germination were used as indices to study the effects of germination ...
Minglang GU, Yingqi GUO, Yongqi YIN, Xudong HE   +3 more
doaj   +1 more source

Anti‐pruritic effect of isothiocyanates: Potential involvement of toll‐like receptor 3 signaling

Pharmacology Research & Perspectives, 2022
The innate immune system has an emerging role as a mediator of neuro‐immune communication and a therapeutic target for itch. Toll‐like receptor 3 (TLR3) plays an important role in itch, as shown in TLR3 knock‐out mice.
Masaki Moriyama, Mitsuhiro Konno, Kanako Serizawa, Natsumi Yuzawa, Yuki Majima, Ikuo Hayashi, Tomohiko Suzuki, Mie Kainoh   +7 more
doaj   +1 more source

Apoptotic Potential of Glucomoringin Isothiocyanate (GMG-ITC) Isolated from Moringa oleifera Lam Seeds on Human Prostate Cancer Cells (PC-3)

Molecules, 2023
Inhibition of several protein pathways involved in cancer cell regulation is a necessary key in the discovery of cancer chemotherapy. Moringa oleifera Lam is often used in traditional medicine for the treatment of various illnesses.
Nurul Ashikin Abd Karim, Aziza Hussein Bakheit Adam, Mohammed Sani Jaafaru, Yaya Rukayadi, Ahmad Faizal Abdull Razis   +4 more
doaj   +1 more source

Enantiopure (S)-butan-2-yl N-(4-x-phenyl)thiocarbamates, x = NO2, OCH3, F, and Cl

Acta Crystallographica Section E: Crystallographic Communications, 2023
The structures of (S)-butan-2-yl N-(4-nitrophenyl)thiocarbamate, C11H14N2O3S, (I), (S)-butan-2-yl N-(4-methoxyphenyl)thiocarbamate, C12H17NO2S, (II), (S)-butan-2-yl N-(4-fluorophenyl)thiocarbamate, C11H14FNOS, (III), and (S)-butan-2-yl N-(4-chlorophenyl ...
Werner Kaminsky, Max Kaganyuk
doaj   +1 more source

Chemical composition of moringa oleifera and cruciferous plants and their anti-inflammatory properties [PDF]

Zbornik Matice Srpske za Prirodne Nauke, 2023
Moringa oleifera Lam. is a tropical tree that has been traditionally used for food, medicine and industrial purposes. All parts of the tree have been utilized and have biological activities, including anti-inflammatory, antibacterial ...
Wolff Khea, Moroianu Sarah, Cho Erica
doaj   +1 more source

Seed Meals from Brassica nigra and Eruca sativa Control Artificial Nosema ceranae Infections in Apis mellifera

Microorganisms, 2021
Nosema ceranae is a widespread parasite responsible for nosemosis Type C in Apis mellifera honey bees, reducing colony survival. The antibiotic fumagillin is the only commercial treatment available, but concerns are emerging about its persistence, safety,
Antonio Nanetti, Luisa Ugolini, Giovanni Cilia, Eleonora Pagnotta, Lorena Malaguti, Ilaria Cardaio, Roberto Matteo, Luca Lazzeri   +7 more
doaj   +1 more source

The H₂S-Donor Erucin Exhibits Protective Effects against Vascular Inflammation in Human Endothelial and Smooth Muscle Cells

Antioxidants, 2021
Preservation of vascular wall integrity against degenerative processes associated with ageing, fat-rich diet and metabolic diseases is a timely therapeutical challenge.
Alma Martelli, Eugenia Piragine, Era Gorica, Valentina Citi, Lara Testai, Eleonora Pagnotta, Luca Lazzeri, Nicola Pecchioni, Valerio Ciccone, Rosangela Montanaro, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Vincenzo Brancaleone, Lucia Morbidelli, Vincenzo Calderone   +14 more
doaj   +1 more source

Antibacterial Activity of Glucomoringin Bioactivated with Myrosinase against Two Important Pathogens Affecting the Health of Long-Term Patients in Hospitals

Molecules, 2013
Glucosinolates (GLs) are natural compounds present in species of the order Brassicales and precursors of bioactive isothiocyanates (ITCs). In the recent years, they have been studied mainly for their chemopreventive as well as novel chemotherapeutics ...
Maria Galuppo, Gina Rosalinda De Nicola, Renato Iori, Pia Dell'Utri, Placido Bramanti, Emanuela Mazzon   +5 more
doaj   +1 more source

Metabolic Fate of Dietary Glucosinolates and Their Metabolites: A Role for the Microbiome

Frontiers in Nutrition, 2021
Robust evidence shows that phytochemicals from cruciferous vegetables, like broccoli, are associated with numerous health benefits. The anti-cancer properties of these foods are attributed to bioactive isothiocyanates (ITCs) and indoles, phytochemicals ...
John A. Bouranis, John A. Bouranis, Laura M. Beaver, Laura M. Beaver, Emily Ho, Emily Ho   +5 more
doaj   +1 more source