Results 181 to 190 of about 172,529 (267)

Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh   +3 more
wiley   +1 more source

Genetic Variation in Chemical Defence Affects Protection of an Herbivorous Insect Against Predation. [PDF]

open access: yesMol Ecol
Körnig J   +9 more
europepmc   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao   +4 more
wiley   +1 more source

Interplay of Ser273 Phosphorylation and K268 and K293 Acetylation in PPARγ: Implications for PPARγ Activation

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) play a critical role in regulating the transcriptional activity of PPARγ, a nuclear receptor central to glucose and lipid homeostasis. Among these, lysine acetylation at K268 and K293 and phosphorylation at S273 are particularly relevant to insulin sensitivity.
Caique Camargo Malospirito   +6 more
wiley   +1 more source

Octreotide Counteracts IFN-γ-Induced Endothelial Inflammation. [PDF]

open access: yesJ Biochem Mol Toxicol
Fakir S   +3 more
europepmc   +1 more source

Transport engineering as a strategy to realize rapeseed's potential as a protein‐rich food

open access: yesPest Management Science, EarlyView.
The heavily pesticide‐dependent rapeseed is an under‐utilized protein source for food owing to anti‐nutritional glucosinolates. Transport engineering technology may reduce glucosinolates in seeds while increasing defense in vegetative parts. Abstract Rapeseed is the world's second‐largest oilseed crop, and the low‐value press cake that remains after ...
Jakob Skytte Thorsen   +2 more
wiley   +1 more source

Field investigation of glucosinolates and morphological traits in mitigating Psylliodes chrysocephala larval infestation through crop varieties and companion planting

open access: yesPest Management Science, EarlyView.
Genotype and cropping system influenced oilseed rape ecophysiological traits, including glucosinolate compounds (glucoraphanin, glucobrassicanapin, and butyl‐glucosinolates) and biomass, which were linked to Psylliodes chrysocephala larval infestation, with varietal effects stronger than faba bean companion planting.
Laurie Magnin   +4 more
wiley   +1 more source

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