Results 1 to 10 of about 56,702 (287)

Nitrile hydratase genes are present in multiple eukaryotic supergroups. [PDF]

PLoS ONE, 2012
Nitrile hydratases are enzymes involved in the conversion of nitrile-containing compounds into ammonia and organic acids. Although they are widespread in prokaryotes, nitrile hydratases have only been reported in two eukaryotes: the choanoflagellate ...
Alan O Marron, Michael Akam, Giselle Walker   +2 more
doaj   +2 more sources

Nitrile versus Latex for Glove Juice Sampling. [PDF]

PLoS ONE, 2014
The objective of this study was to explore the utility of nitrile gloves as a replacement for latex surgical gloves in recovering bacteria from the hands. Two types of nitrile gloves were compared to latex gloves using the parallel streak method. Streaks
Timothy F Landers, Anthony Dent
doaj   +2 more sources

Insight into Enzymatic Nitrile Reduction: QM/MM Study of the Catalytic Mechanism of QueF Nitrile Reductase

ACS Catalysis, 2015
The NADPH-dependent QueF nitrile reductases catalyze the unprecedented four-electron reduction of nitrile to amine. QueF nitrile reductases can be found in the tRNA biosynthetic pathway of many bacteria and are potential antimicrobial drug targets.
Antonio J M Ribeiro, Maria J Ramos, Pedro A Fernandes   +2 more
exaly   +2 more sources

Biochemical characterization of two Brassica oleracea nitrile-specifier proteins [PDF]

Frontiers in Plant Science
Brassica oleracea vegetables (e. g. cabbages) form bioactive isothiocyanates (ITCs) from glucosinolate (GLS) hydrolysis. However, enzymatic activity, acidic pH (below pH 5), and ferrous ions (Fe2+) can promote nitrile release, reducing the ITC amount. In
Kudzai Gracious Mbudu, Kudzai Gracious Mbudu, Katja Witzel, Ute Wittstock, Frederik Börnke, Frederik Börnke, Franziska Sabine Hanschen, Franziska Sabine Hanschen   +7 more
doaj   +2 more sources

Room Temperature Reduction of Titanium Tetrachloride-Activated Nitriles to Primary Amines with Ammonia-Borane

Molecules, 2022
The reduction of a variety of aromatic and aliphatic nitriles, activated by a molar equivalent of titanium tetrachloride, has been achieved at room temperature using ammonia borane as a safe reductant. The corresponding methanamines were isolated in good
P. Veeraraghavan Ramachandran, Abdulkhaliq A. Alawaed   +1 more
doaj   +1 more source

A Proterozoic microbial origin of extant cyanide-hydrolyzing enzyme diversity

Frontiers in Microbiology, 2023
In addition to its role as a toxic environmental contaminant, cyanide has been hypothesized to play a key role in prebiotic chemistry and early biogeochemical evolution.
Sarah L. Schwartz, Sarah L. Schwartz, Sarah L. Schwartz, L. Thiberio Rangel, Jack G. Payette, Gregory P. Fournier   +5 more
doaj   +1 more source

Crystal structures of three homologues with increasing ring size: 2-methoxy-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile, 2-methoxy-4-(thiophen-2-yl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine-3-carbonitrile and 2-methoxy-4-(thiophen-2-yl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile

Acta Crystallographica Section E: Crystallographic Communications, 2023
The title compounds, C15H14N2OS (1a), C16H16N2OS (1b), and C17H18N2OS (1c), form a homologous series in which the size of the saturated ring increases from six- to eight-membered (with four, five and six methylene groups respectively). For 1b and 1c, the
Ali M. S. Hebishy, Galal H. Elgemeie, Lobna M. Gouda, Peter G. Jones   +3 more
doaj   +1 more source

Nitrile-Functionalized Poly(2-oxazoline)s as a Versatile Platform for the Development of Polymer Therapeutics

, 2021
In recent years, polymers bearing reactive groups have received significant interest for biomedical applications. Numerous functional polymer platforms have been introduced, which allow for the preparation of materials with tailored properties via post ...
Kristian Kempe (1308939), Kristian Kempe, Meike N. Leiske, Baptiste Schelle (11564370), Joseph A. Nicolazzo (404936), Zihnil A. I. Mazrad (11564367), Zihnil A. I. Mazrad, Meike N. Leiske (3616979), Baptiste Schelle, Joseph A. Nicolazzo   +9 more
core   +1 more source

B–N/B–H Transborylation: borane-catalysed nitrile hydroboration

Beilstein Journal of Organic Chemistry, 2022
The reduction of nitriles to primary amines is a useful transformation in organic synthesis, however, it often relies upon stoichiometric reagents or transition-metal catalysis.
Filip Meger, Alexander C. W. Kwok, Franziska Gilch, Dominic R. Willcox, Alex J. Hendy, Kieran Nicholson, Andrew D. Bage, Thomas Langer, Thomas A. Hunt, Stephen P. Thomas   +9 more
doaj   +1 more source

Antifungal Activity of Glucosinolate-Derived Nitriles and Their Synergistic Activity with Glucosinolate-Derived Isothiocyanates Distinguishes Various Taxa of Brassicaceae Endophytes and Soil Fungi

Plants, 2023
The glucosinolates of Brassicaceae plants are converted into bioactive isothiocyanates and other volatiles during a challenge by pathogens and other biotic stressors.
Zsolt Szűcs, Tamás Plaszkó, Eszter Bódor, Hajnalka Csoma, Lajos Ács-Szabó, Attila Kiss-Szikszai, Gábor Vasas, Sándor Gonda   +7 more
doaj   +1 more source