Results 21 to 30 of about 121,882 (353)

The Active Site Sulfenic Acid Ligand in Nitrile Hydratases Can Function as a Nucleophile [PDF]

, 2014
Nitrile hydratase (NHase) catalyzes the hydration of nitriles to their corresponding commercially valuable amides at ambient temperatures and physiological pH.
Holz, Richard C., Liu, Dali, Martinez, Salette, Sanishvili, Ruslan, Wu, Rui   +4 more
core   +3 more sources

Synthesis of Highly Substituted Oxazoles through Iodine(III)-Mediated Reactions of Ketones with Nitriles

Molecules, 2012
In the presence of trifluoromethanesulfonic acid (TfOH) or bis(trifluoromethane-sulfonyl)imide (Tf2NH), iodosobenzene (PhI=O) efficiently promoted the reactions of dicarbonyl compounds as well as monocarbonyl compounds with nitriles to give 2,4 ...
Yuji Hanzawa, Akio Saito, Nao Hyodo
doaj   +1 more source

Synthesis of Simplified Azasordarin Analogs as Potential Antifungal Agents [PDF]

, 2019
A new series of simplified azasordarin analogs was synthesized using as key steps a Diels–Alder reaction to generate a highly substituted bicyclo[2.2.1]heptane core, followed by a subsequent nitrile alkylation.
Dockendorff, Chris, Wu, Yibiao
core   +4 more sources

Crystal structure, Hirshfeld surface analysis and interaction energy and DFT studies of 3-{(2Z)-2-[(2,4-dichlorophenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-4-yl}propanenitrile

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compound, C18H12Cl2N2OS, consists of a dihydrobenzothiazine unit linked by a –CH group to a 2,4-dichlorophenyl substituent, and to a propanenitrile unit is folded along the S...N axis and adopts a flattened-boat conformation. The propanenitrile
Nada Kheira Sebbar, Brahim Hni, Tuncer Hökelek, Abdelhakim Jaouhar, Mohamed Labd Taha, Joel T. Mague, El Mokhtar Essassi   +6 more
doaj   +1 more source

Nitrile-assistant eutectic electrolytes for cryogenic operation of lithium ion batteries at fast charges and discharges [PDF]

, 2014
The charge/discharge characteristics of lithium ion batteries at low temperature (LT = -20 ??C) are enhanced by using ethylene carbonate (EC)-based electrolytes with the help of assistant solvents of nitriles. Conventional liquid electrolytes (e.g.
Abu-Lebdeh, Abu-Lebdeh, Bak, Brunet, Ding, Ding, Ding, Dong-Gil Sung, Duncan, Gering, Hyun-Kon Song, Kamaya, Kim, Kim, Lee, Myung-Su Seo, Ruiz, Sazhin, Shiao, Smart, Smart, Smart, Smart, Smart, Smart, Wang, Yoon-Gyo Cho, Young-Soo Kim, Zhang   +28 more
core   +1 more source

Isothiocyanates, Nitriles, and Epithionitriles from Glucosinolates Are Affected by Genotype and Developmental Stage in Brassica oleracea Varieties

Frontiers in Plant Science, 2017
Vegetables of the Brassica oleracea group, such as broccoli, cauliflower, and cabbage, play an important role for glucosinolate consumption in the human diet.
Franziska S. Hanschen, Monika Schreiner
doaj   +1 more source

Covalent Reversible Inhibitors of Cysteine Proteases Containing the Nitrile Warhead: Recent Advancement in the Field of Viral and Parasitic Diseases

Molecules, 2022
In the field of drug discovery, the nitrile group is well represented among drugs and biologically active compounds. It can form both non-covalent and covalent interactions with diverse biological targets, and it is amenable as an electrophilic warhead ...
Simone Brogi, Roberta Ibba, Sara Rossi, Stefania Butini, Vincenzo Calderone, Sandra Gemma, Giuseppe Campiani   +6 more
doaj   +1 more source

X-ray structures of dinuclear copper(I) and polynuclear copper(II) complexes with the 2,4-bis(cyanamido)cyclobutane-1,3-dione dianion [PDF]

, 2006
From the 2,4-bis(cyanamido)cyclobutane-1,3-dione dianion (2,4-NCNsq2−), two copper complexes [Cu2(PPh3)4(PhCN)2(μ-2,4-NCNsq)] · PhCN (1) and [Cu(dien)(μ-2,4-NCNsq) · H2O]n (2) have been synthesized and characterized by IR and electronic absorption ...
Cortadellas, Olivier, Donnadieu, Bruno, Fabre, Paul-Louis, Galibert, Anne-Marie, Soula, Brigitte   +4 more
core   +2 more sources

Direct Regioselective C-H Cyanation of Purines

Molecules, 2023
A direct regioselective C-H cyanation of purines was developed through a sequential triflic anhydride activation, nucleophilic cyanation with TMSCN, followed by a process of base-mediated elimination of triflous acid (CF3SO2H).
Luyong Li, Jie Hu, Yuqing Fu, Xiaolin Shi, Hongguang Du, Jiaxi Xu, Ning Chen   +6 more
doaj   +1 more source

4-(4-Acetyl-5-methyl-1H-1,2,3-triazol-1-yl)benzonitrile: crystal structure and Hirshfeld surface analysis

Acta Crystallographica Section E: Crystallographic Communications, 2018
The title compound, C12H10N4O, comprises a central 1,2,3-triazole ring (r.m.s. deviation = 0.0030 Å) flanked by N-bound 4-cyanophenyl and C-bound acetyl groups, which make dihedral angles of 54.64 (5) and 6.8 (3)° with the five-membered ring, indicating ...
Julio Zukerman-Schpector, Cássio da S. Dias, Ricardo S. Schwab, Mukesh M. Jotani, Edward R. T. Tiekink   +4 more
doaj   +1 more source