Results 1 to 10 of about 247,107 (303)

Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model [PDF]

open access: yes, 2012
Ovarian cancer is the leading cause of cancer related deaths in women. Genetic alterations including overexpression of EGFR play a crucial role in ovarian carcinogenesis.
Joseph Alan Bauer   +4 more
core   +8 more sources

Optimization of Germination Process of Isothiocyanate Enrichment in Broccoli Sprouts by Response Surface Methodology

open access: yesShipin gongye ke-ji, 2022
The accumulation of isothiocyanate in germinated broccoli under ZnSO4-melatonin treatment was optimized. The isothiocyanate content, bud length and fresh weight of broccoli during germination were used as indices to study the effects of germination ...
Minglang GU   +3 more
doaj   +1 more source

Anti‐pruritic effect of isothiocyanates: Potential involvement of toll‐like receptor 3 signaling

open access: yesPharmacology Research & Perspectives, 2022
The innate immune system has an emerging role as a mediator of neuro‐immune communication and a therapeutic target for itch. Toll‐like receptor 3 (TLR3) plays an important role in itch, as shown in TLR3 knock‐out mice.
Masaki Moriyama   +7 more
doaj   +1 more source

Apoptotic Potential of Glucomoringin Isothiocyanate (GMG-ITC) Isolated from Moringa oleifera Lam Seeds on Human Prostate Cancer Cells (PC-3)

open access: yesMolecules, 2023
Inhibition of several protein pathways involved in cancer cell regulation is a necessary key in the discovery of cancer chemotherapy. Moringa oleifera Lam is often used in traditional medicine for the treatment of various illnesses.
Nurul Ashikin Abd Karim   +4 more
doaj   +1 more source

Enantiopure (S)-butan-2-yl N-(4-x-phenyl)thiocarbamates, x = NO2, OCH3, F, and Cl

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2023
The structures of (S)-butan-2-yl N-(4-nitrophenyl)thiocarbamate, C11H14N2O3S, (I), (S)-butan-2-yl N-(4-methoxyphenyl)thiocarbamate, C12H17NO2S, (II), (S)-butan-2-yl N-(4-fluorophenyl)thiocarbamate, C11H14FNOS, (III), and (S)-butan-2-yl N-(4-chlorophenyl ...
Werner Kaminsky, Max Kaganyuk
doaj   +1 more source

Chemical composition of moringa oleifera and cruciferous plants and their anti-inflammatory properties [PDF]

open access: yesZbornik Matice Srpske za Prirodne Nauke, 2023
Moringa oleifera Lam. is a tropical tree that has been traditionally used for food, medicine and industrial purposes. All parts of the tree have been utilized and have biological activities, including anti-inflammatory, antibacterial ...
Wolff Khea, Moroianu Sarah, Cho Erica
doaj   +1 more source

Antibacterial Activity of Glucomoringin Bioactivated with Myrosinase against Two Important Pathogens Affecting the Health of Long-Term Patients in Hospitals

open access: yesMolecules, 2013
Glucosinolates (GLs) are natural compounds present in species of the order Brassicales and precursors of bioactive isothiocyanates (ITCs). In the recent years, they have been studied mainly for their chemopreventive as well as novel chemotherapeutics ...
Maria Galuppo   +5 more
doaj   +1 more source

Metabolic Fate of Dietary Glucosinolates and Their Metabolites: A Role for the Microbiome

open access: yesFrontiers in Nutrition, 2021
Robust evidence shows that phytochemicals from cruciferous vegetables, like broccoli, are associated with numerous health benefits. The anti-cancer properties of these foods are attributed to bioactive isothiocyanates (ITCs) and indoles, phytochemicals ...
John A. Bouranis   +5 more
doaj   +1 more source

Mixed metal nanoparticle assembly and the effect on surface enhanced raman scattering [PDF]

open access: yes, 2010
Here we report the assembly of mixed metal nanoparticles using an oligonucleotide-templated approach. Substitution of one of the gold nanoparticle probes with an analagous silver probe to produce a hetero-metal duplex permitted surface enhanced Raman ...
Alivisatos   +16 more
core   +1 more source

Micellar electrokinetic capillary chromatography—Synchronous monitoring of substrate and products in the myrosinase catalysed hydrolysis of glucosinolates [PDF]

open access: yes, 2006
A micellar electrokinetic capillary chromatography (MECC) method has been developed for monitoring the myrosinase catalysed hydrolysis of 2-hydroxy substituted glucosinolates and the simultaneous formation of the corresponding degradation products ...
Bellostas, Natalia   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy