Results 321 to 330 of about 266,552 (386)

In Vitro Live Cell Imaging Reveals Nuclear Dynamics and Role of the Cytoskeleton During Asymmetric Division of Pollen Mitosis I in Nicotiana Benthamiana

Cytoskeleton, EarlyView.
ABSTRACT Pollen is a male gametophyte of angiosperms. Following meiosis, the microspore undergoes an asymmetric division called pollen mitosis I (PMI), which produces two cells of different sizes: a large vegetative cell and a small generative cell. Polarized nuclear migration and positioning during PMI are important for successful pollen development ...
Yoko Mizuta, Masako Igarashi, Tomomi Shinagawa, Ikuma Kaneshiro, Haoto Anan, Daisuke Kurihara   +5 more
wiley   +1 more source

Open-Label Interventional Study in Healthy Volunteers to Evaluate NO-Mediated Vasodilation by Dermal Allyl Isothiocyanate Challenge and Whole-Body Heat Stress. [PDF]

J Exp Pharmacol
van Ruissen MCE, van Kraaij SJW, Gal P, Bakker WA, Hijma HJ, Groeneveld GJ, de Kam ML, Burggraaf J, Moerland M.   +8 more
europepmc   +1 more source

Synthesis and 64Cu‐Radiolabeling Strategies of Small Organic Radioconjugates Based on the AMD070 Scaffold

ChemMedChem, EarlyView.
Two novel 64Cu‐radioconjugates have been prepared, based on the AMD070 scaffold as a targeting unit and cyclam‐based te1pa chelator, for future applications in positron emission tomography imaging. Synthesis of ligands and their 64Cu‐radiolabeling are described herein.
Marie M. Le Roy, Patricia Le Saëc, Michel Chérel, Alain Faivre‐Chauvet, Thibault Troadec, Raphaël Tripier   +5 more
wiley   +1 more source

Mannitol-facilitated entry of vancomycin into the central nervous system inhibits neuroinflammation in a rat model of MRSA intracranial infection by modulating brain endothelial cells. [PDF]

World J Emerg Med
Wen Y, Su Z, Zhu H, Liu M, Li Z, Zhang S, Cai S, Tang J, Ding H, Zeng H.   +9 more
europepmc   +1 more source

NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES

ChemMedChem, Accepted Article.
Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti, Concetta Altamura, Simone Dell’Atti, Jean-François Desaphy, Ilaria Saltarella   +4 more
wiley   +1 more source

Effect of Benzyl Isothiocyanate on Anaplastic Thyroid Cancer Evaluated by Network Pharmacology Combined with Experiments. [PDF]

ACS Omega
Ma C, Zhang Q, Wang Y, Li D, Zhang H, Jia Q, Zheng W, Tan J, Xu K, Yang L, Meng Z.   +10 more
europepmc   +1 more source

The Role of Five‐Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview

ChemMedChem, Accepted Article.
Over the past decades extensive scientific research in the fields of chemistry and pharmaceutical chemistry has led to the synthesis and study of numerous chemical compounds with diverse therapeutic applications. Many of these compounds feature heterocyclic aromatic structures, including six‐, five‐, and four‐membered rings.
Claudia Finamore, Carmen Festa, Rosa Barbato, Stefano Fiorucci, Angela Zampella, Simona De Marino   +5 more
wiley   +1 more source

Xylanase and stimbiotic supplementation improve broilers performance and nutrient digestibility across both wheat-barley and corn-based diets. [PDF]

Poult Sci
Toghyani M, Kim E, Macelline SP, González-Ortiz G, Barekatain R, Liu SY.   +5 more
europepmc   +1 more source

Further Investigation Into an Environmental Source for Aminorex

Drug Testing and Analysis, EarlyView.
The results provide evidence that resedine is an intermediary compound between barbarin and aminorex in horses and that resedine can be used as a biomarker to eliminate the reporting of aminorex positives originating from the ingestion of plants from the Brassicaceae family.
Lydia Brooks, Michael Ryan, Erin McCosham, Devan Loganathan   +3 more
wiley   +1 more source

Active peptides of TSP-1 inhibit retinal angiogenesis through the CD36 pathway in a rat model of choroidal neovascularization. [PDF]

PLoS One
Li Y, Deng A, Jiao K, Yan J, Zuo W, Dong Y, Xu W, Li Y, Guo C, Chen M, Tian R, Hu Z.   +11 more
europepmc   +1 more source