Results 111 to 120 of about 2,779,234 (237)

Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine

Small, EarlyView.
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa, Lorenzo Arnaboldi, Veronica De Giorgis, Marco Ghirimoldi, Elettra Barberis, Marco Brucale, Francesco Valle, Mario Malerba, Marta Vallino, Angelo Musicò, Roberto Frigerio, Alessandro Gori, Vera Mugoni, Claudia Voena, Roberto Pisano, Fabrizio Pirri, Silvia Arpicco, Marcello Manfredi, Tania Limongi   +18 more
wiley   +1 more source

Survey of current maintenance intravenous fluids prescribing practices among Egyptian pediatricians

Egyptian Pediatric Association Gazette
Background Recent research has firmly linked the administration of hypotonic fluids with the incidence of hospital-acquired hyponatremia in pediatric patients.
Alyaa Ahdy Abdelaziz, Hafez Mahmoud Bazaraa, Sherif Reda Omar, Rasha Ashmawy, Yousra A. El-Maradny, Ramy Mohammed Ghazy   +5 more
doaj   +1 more source

Enteral electrolyte solutions with different osmolarities administered in a continuous flow in newborn calves

Ciência Rural
: This study compared the effects of enteral electrolyte solutions with different osmolarities in Holstein cattle. Eighteen newborn calves were evenly divided into three groups and administered the following treatments: hypotonic electrolyte solution ...
José Dantas Ribeiro Filho, Waleska de Melo Ferreira Dantas, Antônio de Pádua Lima, Rinaldo Batista Viana, Micheline Ozana da Silva, Pedro Ancelmo Nunes Ermita, Gláucia Matos Marques da Silva, Bruna Maria Ribeiro, Caio Monteiro Costa, Lorena Chaves Monteiro   +9 more
doaj   +1 more source

Generalized continuous isotonic regression

The standard isotonic regression of a vector in is the solution to a least squares projection problem on the cone of vectors with 'increasing components' in .
Groeneboom, Piet, Jongbloed, Geurt
core  

Humidity Ramp Protocols Systematically Underestimate Human Heat Tolerance Limits

Safety Science and Technology, EarlyView.
Short dwell times in humidity‐ramp protocols (Δt/τ≪1 ${\Delta }t/\tau \mathit{\ll }1$) prevent human core temperature from reaching equilibrium, causing premature inflection points and systematic underestimation of critical environmental limits by ∼3°C–4°C.
Fèlix Faming Wang, Yi Xu, Haojian Wang, Min Cui, Xue Hou, Boan Wei, Xiong Shen   +6 more
wiley   +1 more source

Hypotonic and isotonic intravenous maintenance fluids in hospitalized controlled trial.

, 2019
https://bmjpaedsopen.bmj.com/content/bmjpo/3/1/e000385.full.pdfAbstract Objective: To compare the changes in serum sodium and acid/base status in patients receiving hypotonic and isotonic solutions.
Siaba, Alejandro., Torres, Silvio., Rocca, Manuel., Schnitzler, Eduardo., Sticco, Nicolás., Ioister, Thomas.   +5 more
core   +1 more source

Determination of water permeability in stress‐free lipid membranes through time‐resolved small‐angle neutron scattering

Journal of Applied Crystallography, EarlyView.
Time‐resolved small‐angle neutron scattering with rapid contrast variation enables direct non‐invasive measurement of water permeation kinetics and membrane structure under iso‐osmotic conditions for lipid membranes.Accurate quantification of water permeation across lipid membranes is challenging, with reported permeability values varying widely due to
Moritz P. K. Frewein, Ursula Perez-Salas, O. H. Samuli Ollila, Georg Pabst, Lionel Porcar   +4 more
wiley   +1 more source

Phloroglucinol inhibits human ureteral contractions via activation of cAMP‐PKA pathway

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Phloroglucinol is used to treat renal colic, especially when non‐steroidal anti‐inflammatory drugs are contraindicated. This study aimed to clarify its mechanism by examining effects on human ureteral contractility and underlying signalling pathways. Experimental Approach Urinary levels of neurokinin A (NKA), substance P
Hanwen Liu, Ruize Xu, Zihan Guan, Lei Liu, Guangda Lv, Weibo Chen, Jiliang Wen, Jianing Liu, Jieke Yan, Fangxin Gong, Pan Xiao, Xiulin Zhang, Lei Zhang   +12 more
wiley   +1 more source

Connectedness in isotonic spaces

, 2006
An isotonic space (X, cl) is a set X with isotonic operator cl: P (X)\to P (X) which satisfies cl (\emptyset)=\emptyset and cl (A)\subseteq cl (B) whenever A\subseteq B\subseteq X.
Habil, Eissa D., Elzenati, Khalid A.
core  

Decellularised Corneal Stromal Lamina With or Without Autologous Adipose‐Derived Adult Stem Cells for Advanced Keratoconus: 1‐Year Results of a Phase I/IIa Clinical Trial

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To report the 1‐year clinical outcomes of decellularised human corneal stromal lamina implantation, with or without autologous adipose‐derived adult stem cells (ADASCs), for advanced keratoconus in a European cohort. Methods In this prospective, randomised Phase I/IIa trial, 10 eyes of 10 patients were allocated to decellularised ...
Hao Zhang, Jorge L. Alió del Barrio, Alejandra E. Rodriguez, Rafael I. Barraquer, Francisco Arnalich‐Montiel, David Mingo‐Botín, María Eugenia Fernández Santos, Jorge L. Alió   +7 more
wiley   +1 more source