Results 151 to 160 of about 23,169 (258)

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis   +9 more
wiley   +1 more source

Osmotic pressure-induced calcium response states. [PDF]

open access: yesFEBS Open Bio
Gao Z, Naruse K, Morimatsu M.
europepmc   +1 more source

Synthesis and Characterization of Tritium‐Labeled Neuropeptide Y Y5 Receptor Ligands Derived From CGP71683A

open access: yesArchiv der Pharmazie, Volume 359, Issue 8, August 2026.
From a synthesized series of 2,4‐diaminoquinazoline‐type Y5R ligands, three were prepared as tritium‐labeled compounds and characterized by saturation equilibrium binding at HEC‐1B‐hY5R cells. [3H]32 was further applied in a competition binding assay. High non‐specific binding of the radioligands prompted investigation of material‐dependent adsorption.
Franziska Schettler   +2 more
wiley   +1 more source

Numerical and Experimental Assessment of Oxygen Distribution in a Perfusion Bioreactor to Mimic the Osteochondral Niche

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 8, Page 2139-2152, August 2026.
ABSTRACT Oxygen supply is a critical parameter in 3D cell cultivation using bioreactors. Since bioreactor designs often prioritise practical constraints, understanding the oxygen supply dynamics of the media is crucial for achieving either uniform or spatially controlled oxygen delivery.
Franziska Alt   +4 more
wiley   +1 more source

Estrogen Receptor Beta Activation Coordinates Liver Lipid Remodeling and Metabolic Fluxes, Preventing Lipotoxicity

open access: yesComprehensive Physiology, Volume 16, Issue 4, August 2026.
ERβ activation restores glucose and lipid homeostasis by remodeling the hepatic lipidome. Mechanistically, it promotes complete fatty acid oxidation and decreases Acetyl‐CoA levels, leading to reduced ketogenesis and lipotoxicity, as demonstrated through in vivo and in vitro approaches.
Debora Santos Rocha   +9 more
wiley   +1 more source

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