Results 21 to 30 of about 120,968 (266)

Insights Into the Known 13C Depletion of Methane—Contribution of the Kinetic Isotope Effects on the Serine Hydroxymethyltransferase Reaction

Frontiers in Chemistry, 2022
We determined the kinetic isotope effect on the serine hydroxymethyltransferase reaction (SHMT), which provides important C1 metabolites that are essential for the biosynthesis of DNA bases, O-methyl groups of lignin and methane. An isotope effect on the
Gerd Gleixner
doaj   +1 more source

1,2-3H-Cholesterol as a tracer in studies of human cholesterol metabolism

Journal of Lipid Research, 1967
1,2-3H-Cholesterol was fed to a subject together with 4-14C-cholesterol at a known 3H/14C ratio. The ratio was satisfactorily preserved in cholesterol recovered from plasma, red cells, and bile, and in bile acids of bile.Isotopic fractionation was seen ...
Peter D.S. Wood, Daphne Myers, Yuen-Ling Lee, Ryuzo Shioda, Laurance W. Kinsell   +4 more
doaj   +1 more source

Experimental study and gyrokinetic simulations of isotope effects on core heat transport in JET tokamak deuterium and tritium plasmas

Nuclear Fusion
This paper presents a study on the dependence of the ion temperature stiffness on the plasma main ion isotope mass in JET ITER-like wall and C wall discharges.
D. Brioschi, P. Mantica, A. Mariani, N. Bonanomi, E. Delabie, J. Garcia, N. Hawkes, I. Jepu, D. Keeling, E. Lerche, E. Litherland-Smith, C.F. Maggi, S. Menmuir, G. Szepesi, D. Taylor, D. Van Eester, JET Contributors   +16 more
doaj   +1 more source

The influence of deuterium‑depleted water Larsen D100 on seed germination parameters in cereal, oilseed, and legume crops

Siberian Journal of Life Sciences and Agriculture
Background.  The study aimed to investigate the species-specific effects of deuterium-depleted water (Larsen D100,
Denis A. Kozyrev, Andrey G. Polyakov, Mary Yu. Odabashyan, Anastasiya V. Olshevskaya, Arina A. Eroshenko, Dmitry N. Savenkov, Natalia A. Kulikova   +6 more
doaj   +1 more source

Deuterated Arachidonic Acids Library for Regulation of Inflammation and Controlled Synthesis of Eicosanoids: An In Vitro Study

Molecules, 2018
The synthesis of signal lipids, including eicosanoids, is not fully understood, although it is key to the modulation of various inflammatory states.
Dmitry V. Chistyakov, Ivan S. Filimonov, Nadezhda V. Azbukina, Sergei V. Goriainov, Viktor V. Chistyakov, Maksim A. Fomich, Andrei V. Bekish, Vadim V. Shmanai, Marina G. Sergeeva, Mikhail S. Shchepinov   +9 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Isotope effect suggests site‐specific nonadiabaticity on Ge(111)c(2×8)

Natural Sciences
Energy transferred in atom‐surface collisions typically depends strongly on projectile mass, an effect that can be experimentally detected by isotopic substitution.
Kerstin Krüger, Yingqi Wang, Lingjun Zhu, Bin Jiang, Hua Guo, Alec M. Wodtke, Oliver Bünermann   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structure and superconductivity of isotope-enriched boron-doped diamond

Science and Technology of Advanced Materials, 2008
Superconducting boron-doped diamond samples were synthesized with isotopes of 10B, 11B, 13C and 12C. We claim the presence of a carbon isotope effect on the superconducting transition temperature, which supports the 'diamond-carbon'-related nature of ...
Evgeny A Ekimov, Vladimir A Sidorov, Andrey V Zoteev, Yury B Lebed, Joe D Thompson and Sergey M Stishov
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source