Envelope: interactive software for modeling and fitting complex isotope distributions [PDF]
BMC Bioinformatics, 2008 Background An important aspect of proteomic mass spectrometry involves quantifying and interpreting the isotope distributions arising from mixtures of macromolecules with different isotope labeling patterns.
Michael T Sykes +23 more
core +4 more sources
The Rules of Human T Cell Fate in vivo. [PDF]
Frontiers in Immunology, 2020 The processes governing lymphocyte fate (division, differentiation, and death), are typically assumed to be independent of cell age. This assumption has been challenged by a series of elegant studies which clearly show that, for murine cells in vitro ...
Asquith, B +8 more
core +3 more sources
Laboratory evaluation of stable isotope labeling of Culicoides (Diptera: Ceratopogonidae) for adult dispersal studies. [PDF]
Parasites & Vectors, 2019 BackgroundStable isotope labeling is a promising method for use in insect mark-capture and dispersal studies. Culicoides biting midges, which transmit several important animal pathogens, including bluetongue virus (BTV) and epizootic hemorrhagic disease ...
Gerry, Alec C +6 more
core +3 more sources
Stable isotopic labeling in proteomics [PDF]
PROTEOMICS, 2008 AbstractLabeling of proteins and peptides with stable heavy isotopes (deuterium, carbon‐13, nitrogen‐15, and oxygen‐18) is widely used in quantitative proteomics. These are either incorporated metabolically in cells and small organisms, or postmetabolically in proteins and peptides by chemical or enzymatic reactions.
Gevaert, Kris +5 more
openaire +6 more sources
Hydrogen isotope labeling unravels origin of soil-bound organic contaminant residues in biodegradability testing. [PDF]
Nat CommunBiodegradability testing in soil helps to identify safe synthetic organic chemicals but is still obscured by the formation of soil-bound ‘non-extractable’ residues (NERs).
Lennartz S +4 more
europepmc +2 more sources
15N Metabolic Labeling Quantification Workflow in Arabidopsis Using Protein Prospector
Frontiers in Plant Science, 2022 Metabolic labeling using stable isotopes is widely used for the relative quantification of proteins in proteomic studies. In plants, metabolic labeling using 15N has great potential, but the associated complexity of data analysis has limited its usage ...
Ruben Shrestha +7 more
doaj +1 more source
Isotope Calculation Gadgets: A Series of Software for Isotope-Tracing Experiments in Garuda Platform
Metabolites, 2022 Isotope tracing is a powerful technique for elucidating intracellular metabolism. Experiments utilizing this technique involve various processes, such as the correction of natural isotopes.
Nobuyuki Okahashi +3 more
doaj +1 more source
mfapy: An open-source Python package for 13C-based metabolic flux analysis
Metabolic Engineering Communications, 2021 13C-based metabolic flux analysis (13C-MFA) is an essential tool for estimating intracellular metabolic flux levels in metabolic engineering and biology.
Fumio Matsuda +6 more
doaj +1 more source
Microbiology Research, 2023 The use of stable isotope-labeled polymers in in situ biodegradation tests provides detailed information on the degradation process. As isotope-labeled raw chemicals are generally expensive, it is desirable to prepare polymer samples with high production
Ramamoorthi M. Sivashankari +2 more
doaj +1 more source
Metabolic Flux Analysis—Linking Isotope Labeling and Metabolic Fluxes
Metabolites, 2020 Metabolic flux analysis (MFA) is an increasingly important tool to study metabolism quantitatively. Unlike the concentrations of metabolites, the fluxes, which are the rates at which intracellular metabolites interconvert, are not directly measurable ...
Yujue Wang +4 more
doaj +1 more source