Results 1 to 10 of about 100,704 (351)

Laboratory evaluation of stable isotope labeling of Culicoides (Diptera: Ceratopogonidae) for adult dispersal studies [PDF]

open access: yesParasites & Vectors, 2019
Background Stable isotope labeling is a promising method for use in insect mark-capture and dispersal studies. Culicoides biting midges, which transmit several important animal pathogens, including bluetongue virus (BTV) and epizootic hemorrhagic disease
Emily G. McDermott   +6 more
doaj   +3 more sources

The Rules of Human T Cell Fate in vivo [PDF]

open access: yesFrontiers in Immunology, 2020
The processes governing lymphocyte fate (division, differentiation, and death), are typically assumed to be independent of cell age. This assumption has been challenged by a series of elegant studies which clearly show that, for murine cells in vitro ...
Pedro Costa del Amo   +9 more
doaj   +3 more sources

Hydrogen isotope labeling unravels origin of soil-bound organic contaminant residues in biodegradability testing [PDF]

open access: yesNature Communications
Biodegradability testing in soil helps to identify safe synthetic organic chemicals but is still obscured by the formation of soil-bound ‘non-extractable’ residues (NERs).
Sophie Lennartz   +4 more
doaj   +2 more sources

15N Metabolic Labeling Quantification Workflow in Arabidopsis Using Protein Prospector

open access: yesFrontiers in Plant Science, 2022
Metabolic labeling using stable isotopes is widely used for the relative quantification of proteins in proteomic studies. In plants, metabolic labeling using 15N has great potential, but the associated complexity of data analysis has limited its usage ...
Ruben Shrestha   +7 more
doaj   +1 more source

Isotope Calculation Gadgets: A Series of Software for Isotope-Tracing Experiments in Garuda Platform

open access: yesMetabolites, 2022
Isotope tracing is a powerful technique for elucidating intracellular metabolism. Experiments utilizing this technique involve various processes, such as the correction of natural isotopes.
Nobuyuki Okahashi   +3 more
doaj   +1 more source

mfapy: An open-source Python package for 13C-based metabolic flux analysis

open access: yesMetabolic Engineering Communications, 2021
13C-based metabolic flux analysis (13C-MFA) is an essential tool for estimating intracellular metabolic flux levels in metabolic engineering and biology.
Fumio Matsuda   +6 more
doaj   +1 more source

Poly(3-Hydroxybutyrate) Biosynthesis from [U-13C6]D-Glucose by Ralstonia eutropha NCIMB 11599 and Recombinant Escherichia coli

open access: yesMicrobiology Research, 2023
The use of stable isotope-labeled polymers in in situ biodegradation tests provides detailed information on the degradation process. As isotope-labeled raw chemicals are generally expensive, it is desirable to prepare polymer samples with high production
Ramamoorthi M. Sivashankari   +2 more
doaj   +1 more source

Metabolic Flux Analysis—Linking Isotope Labeling and Metabolic Fluxes

open access: yesMetabolites, 2020
Metabolic flux analysis (MFA) is an increasingly important tool to study metabolism quantitatively. Unlike the concentrations of metabolites, the fluxes, which are the rates at which intracellular metabolites interconvert, are not directly measurable ...
Yujue Wang   +4 more
doaj   +1 more source

gQuant, an Automated Tool for Quantitative Glycomic Data Analysis

open access: yesFrontiers in Chemistry, 2021
MALDI-MS-based glycan isotope labeling methods have been effectively and widely used for quantitative glycomics. However, interpretation of the data produced by MALDI-MS is inaccurate and tedious because the bioinformatic tools are inadequate.
Jiangming Huang   +7 more
doaj   +1 more source

ISOTOPICS – ISOTOPIC LABELING FOR DRUG INNOVATION – H2020 [PDF]

open access: yesImpact, 2017
ISOTOPICS (H2020 - Marie Sklodowska-Curie Actions - Innovative Training Network; grant number 675071) combines researchers and industry in an innovative effort to de-risk drug development, create new tools for medicine and train first-class radiochemists with dual academic-industrial expertise.
Dugave, Christophe, Hinsinger, Karen
openaire   +2 more sources

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