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Hydrogen isotope labeling unravels origin of soil-bound organic contaminant residues in biodegradability testing [PDF]
Nature CommunicationsBiodegradability testing in soil helps to identify safe synthetic organic chemicals but is still obscured by the formation of soil-bound ‘non-extractable’ residues (NERs).
Sophie Lennartz +4 more
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15N Metabolic Labeling Quantification Workflow in Arabidopsis Using Protein Prospector
Frontiers in Plant Science, 2022 Metabolic labeling using stable isotopes is widely used for the relative quantification of proteins in proteomic studies. In plants, metabolic labeling using 15N has great potential, but the associated complexity of data analysis has limited its usage ...
Ruben Shrestha +7 more
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Isotope Calculation Gadgets: A Series of Software for Isotope-Tracing Experiments in Garuda Platform
Metabolites, 2022 Isotope tracing is a powerful technique for elucidating intracellular metabolism. Experiments utilizing this technique involve various processes, such as the correction of natural isotopes.
Nobuyuki Okahashi +3 more
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mfapy: An open-source Python package for 13C-based metabolic flux analysis
Metabolic Engineering Communications, 2021 13C-based metabolic flux analysis (13C-MFA) is an essential tool for estimating intracellular metabolic flux levels in metabolic engineering and biology.
Fumio Matsuda +6 more
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Microbiology Research, 2023 The use of stable isotope-labeled polymers in in situ biodegradation tests provides detailed information on the degradation process. As isotope-labeled raw chemicals are generally expensive, it is desirable to prepare polymer samples with high production
Ramamoorthi M. Sivashankari +2 more
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ISOTOPICS – ISOTOPIC LABELING FOR DRUG INNOVATION – H2020 [PDF]
Impact, 2017 ISOTOPICS (H2020 - Marie Sklodowska-Curie Actions - Innovative Training Network; grant number 675071) combines researchers and industry in an innovative effort to de-risk drug development, create new tools for medicine and train first-class radiochemists with dual academic-industrial expertise.
Dugave, Christophe, Hinsinger, Karen
openaire +2 more sources
Metabolic Flux Analysis—Linking Isotope Labeling and Metabolic Fluxes
Metabolites, 2020 Metabolic flux analysis (MFA) is an increasingly important tool to study metabolism quantitatively. Unlike the concentrations of metabolites, the fluxes, which are the rates at which intracellular metabolites interconvert, are not directly measurable ...
Yujue Wang +4 more
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gQuant, an Automated Tool for Quantitative Glycomic Data Analysis
Frontiers in Chemistry, 2021 MALDI-MS-based glycan isotope labeling methods have been effectively and widely used for quantitative glycomics. However, interpretation of the data produced by MALDI-MS is inaccurate and tedious because the bioinformatic tools are inadequate.
Jiangming Huang +7 more
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Journal of Magnetic Resonance Open, 2022 In this work a rapid RNA assignment approach by combining chemical and enzymatic 13C and 15N stable isotope labeling is introduced. We exemplify the assignment strategy for imino N1H1 purine and N3H3 pyrimidine and aromatic C6H6 pyrimidine, C8H8 purine ...
David Klingler +3 more
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Scientific Data, 2023 Metabolic stable isotope labeling with heavy water followed by liquid chromatography coupled with mass spectrometry (LC-MS) is a powerful tool for in vivo protein turnover studies.
Henock M. Deberneh +8 more
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