Results 211 to 220 of about 100,704 (351)

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

Advanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng, Haoran Sun, Jin Cheng, Ruyi Zhao, Jianzhu Xie, Yanwei Song, Yucui Zhao, Chenwei Lin, Binjie Hu, Yanping Gong, Jun Lin, Sijia He, Yuntao Luo, Minghui Zhao, Yiwei Wang, Ming Jiao, Yuqin Yang, Jikun Li, Shujie Xia, Chuanyuan Li, Qian Huang   +20 more
wiley   +1 more source

Stable Isotope Labeling in Bacteria Enables Characterization and Quantification of Frataxin Protein in a Friedreich's Ataxia Zebrafish Model. [PDF]

Anal Chem
Rojsajjakul T, Do W, Wilson RB, Blair IA.   +3 more
europepmc   +1 more source

Carbon mass balance model to investigate biochar and activated carbon amendment effects on the biodegradation of stable-isotope labeled toluene in gravelly sand

, 2020
George Mangse, David Werner
openalex   +1 more source

A Generalized Approach for Distal C–H Arylation of Organic Building Blocks: Unveiling the Role of Counter Anion

Advanced Science, EarlyView.
We report a general strategy for meta‐selective C–H arylation using aryl iodides and a Pd(II)/Pd(IV) catalytic system guided by a removable directing group. DFT and experimental studies reveal that counter anion tuning (acetate to trifluoroacetate) significantly enhances selectivity.
Jagrit Grover, Gaurav Prakash, Astam Mandal, Devika Ghosh, Siddhartha Maiti, Claire Empel, Debabrata Maiti   +6 more
wiley   +1 more source

Segmental Isotope Labeling of the Prion Protein: Identification of a Key Residue for Copper-Mediated Interdomain Structure. [PDF]

ACS Chem Biol
Pavlovici FA, Singewald K, Kaplan S, Chen E, Millhauser GL.   +4 more
europepmc   +1 more source

Stable Isotope Labeling-Based Nontargeted Strategy for Characterization of the In Vitro Metabolic Profile of a Novel Doping BPC-157 in Doping Control by UHPLC-HRMS. [PDF]

Molecules, 2023
Tian T, Jing J, Li Y, Wang Y, Deng X, Shan Y.   +5 more
europepmc   +1 more source

Computation‐Guided Dual‐Site Electrocatalysts for Record‐Performance Nitrite‐to‐Ammonia Conversion

Advanced Science, EarlyView.
Designing Cu doped ZnO catalysts for NO2RR via first principles calculation and boosting electrocatalytic nitrite reduction through Cu‐ZnO synergistic deoxygenation, hydrogenation, and NH3 desorption. Cu doping elevates the d‐band center of Zn, strengthening *NO2 binding and deoxygenation, while ZnO sites regulate water adsorption and dissociation ...
Hui Zhang, Haiyan Duan, Donglin Han, Zhenlin Wang, Xingchi Li, Dengchao Peng, Lupeng Han, Tianting Pang, Evangelina Pensa, Wenqiang Qu, Yongjie Shen, Haotian Wang, Wei Ren, Ming Xie, Emiliano Cortés, Dengsong Zhang   +15 more
wiley   +1 more source

Triple labeling of metabolites for metabolome analysis (TLEMMA): a stable isotope labeling approach for metabolite identification and network reconstruction. [PDF]

Plant J
Dong Y, Feldberg L, Wang Y, Heinig U, Rogachev I, Aharoni A.   +5 more
europepmc   +1 more source

Turnover and replication analysis by isotope labeling (TRAIL) reveals the influence of tissue context on protein and organelle lifetimes. [PDF]

Mol Syst Biol, 2023
Hasper J, Welle K, Hryhorenko J, Ghaemmaghami S, Buchwalter A.   +4 more
europepmc   +1 more source

Use of stable isotope-labeled fatty acids to measure desaturase activities with negative chemical ionization GC-MS

Youenn Launay, Iwan Jan, Vincent Ciesielski, L. T. N. Hue, Mélodie Succar, Léa Fret, Thomas Guerbette, Karima Begriche, Philippe Legrand, Daniel Catheline, Manuel Vlach, Vincent Rioux   +11 more
openalex   +1 more source