Results 221 to 230 of about 45,524 (260)

Isotopic labeling of milk disialogangliosides (GD3)

Chemistry and Physics of Lipids, 2016
The most abundant ganglioside group in both human milk and bovine milk during the first postnatal week is ganglioside GD3. This group of disialogangliosides forms up to 80% of the total ganglioside content of colostrum. Although dietary gangliosides have shown biological activity such as improvement of cognitive development, gastrointestinal health ...
Mariza Gomes Reis, Rodrigo Bibiloni, Paul McJarrow, Alastair MacGibbon, Bertram Fong, Shalome Bassett, Nicole Roy, Marlon Martins dos Reis   +7 more
openaire   +2 more sources

Isotopic labelings for mechanistic studies

The intricate mechanisms in the biosynthesis of terpenes belong to the most challenging problems in natural product chemistry. Methods to address these problems include the structure-based site-directed mutagenesis of terpene synthases, computational approaches, and isotopic labeling experiments. The latter approach has a long tradition in biosynthesis
Houchao, Xu, Jeroen S, Dickschat
openaire   +2 more sources

Isotope Labeling of Proteins in Insect Cells

2015
Protein targets of contemporary research are often membrane proteins, multiprotein complexes, secreted proteins, or other proteins of human origin. These are difficult to express in the standard expression host used for most nuclear magnetic resonance (NMR) studies, Escherichia coli.
Lukasz, Skora, Binesh, Shrestha, Alvar D, Gossert   +2 more
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Optimal Design of Isotope Labeling Experiments

2013
Stable isotope labeling experiments (ILE) constitute a powerful methodology for estimating metabolic fluxes. An optimal label design for such an experiment is necessary to maximize the precision with which fluxes can be determined. But often, precision gained in the determination of one flux comes at the expense of the precision of other fluxes, and an
Hong, Yang, Dominic E, Mandy, Igor G L, Libourel   +2 more
openaire   +2 more sources

ICPL—Isotope-Coded Protein Label

2008
Stable isotope labeling in combination with mass spectrometry has emerged as a powerful tool to identify and relatively quantify thousands of proteins within complex protein mixtures. Here we describe a method, termed isotope-coded protein label (ICPL), which is capable of high-throughput quantitative proteome profiling on a global scale.
openaire   +3 more sources

Chemical isotope labeling for quantitative proteomics

Mass Spectrometry Reviews, 2023
Xiaobo Tian, Hjalmar P Permentier, Rainer Bischoff   +2 more
exaly  

Isotopic labelling of proanthocyanidins

1997
International ...
Deprez, S., Buffnoir, S., Scalbert, Augustin, Rolando, Christian   +3 more
openaire   +2 more sources

Isotope labeling strategies of glycans for mass spectrometry-based quantitative glycomics

Microchemical Journal, 2021
Jae－Min Lim
exaly  

Radiopharmaceuticals labelled with bromine isotopes

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, 1986
B, Maziere, C, Loc'h
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Advances and perspectives in chemical isotope labeling-based mass spectrometry methods for metabolome and exposome analysis

TrAC - Trends in Analytical Chemistry, 2023
Shuyun Zhu, Xian-En Zhao
exaly