Results 41 to 50 of about 92,950 (293)

Nitrogen uptake and internal recycling in Zostera marina exposed to oyster farming: eelgrass potential as a natural biofilter [PDF]

, 2016
Oyster farming in estuaries and coastal lagoons frequently overlaps with the distribution of seagrass meadows, yet there are few studies on how this aquaculture practice affects seagrass physiology.
A Alexandre, A Alexandre, A Buhmann, A Cabello-Pasini, A Neori, Ana Alexandre, BJ Dudley, BR Dumbauld, BW Touchette, BW Touchette, C Buzzelli, CA Simenstad, CD Cornelisen, CM Maier, DH Ward, DM Booth, E Wagner, ET Apostolaki, FT Short, G Lepoint, G Lepoint, H Iizumi, H Peterson, H Peterson, HF Vinther, HF Vinther, HM Tallis, I Olivé, J Forde, J Stapel, J Stapel, J Terrados, J Zertuche-González, JA Vonk, JC Zieman, JM Burkholder, JM Hernández-Ayón, JM Ruiz, JM Sandoval-Gil, Jose Sandoval-Gil, JR Kelly, JW Fourqurean, K-S Lee, KJ McGlathery, L Rubio, LK Korhonen, LM Rasmusson, LM Wisehart, M Alkhatib, M Poumian-Tapia, M Ribas-Ribas, M Yamamuro, MA Hemminga, MA Hemminga, MA Hemminga, MA Skinner, MF Pedersen, MF Pedersen, ML Kellogg, N Hasegawa, N Marbá, O Invers, O Invers, RA Everett, RD Evans, Rui Santos, S García-Esquivel, S Sharma, T Alcoverro, T Alcoverro, TB Coplen, TBH Reusch, TJ Hoellein, VF Camacho-Ibar, Víctor F. Camacho-Ibar   +74 more
core   +1 more source

Synthesis of isotopically labelled ubiquinones

Tetrahedron Letters, 1992
Abstract Ubiquinones ( 1 ) of various chain lengths have been synthesized. The key step involves the condensation of a long chain polyunsaturated alcohol onto an aromatic intermediate. The synthetic methodology allows for the incorporation of isotopic labels in the methoxy groups attached to the ring portion of the molecule.
Duralski, A, Watts, A
openaire   +2 more sources

Chemoenzymatic Assembly of Isotopically Labeled Folates [PDF]

Journal of the American Chemical Society, 2017
Pterin-containing natural products have diverse functions in life, but an efficient and easy scheme for their in vitro synthesis is not available. Here we report a chemoenzymatic 14-step, one-pot synthesis that can be used to generate 13C- and 15N-labeled dihydrofolates (H2F) from glucose, guanine, and p-aminobenzoyl-l-glutamic acid.
Antonio Angelastro, William M. Dawson, Louis Y. P. Luk, E. Joel Loveridge, Rudolf K. Allemann   +4 more
openaire   +6 more sources

The topology of metabolic isotope labeling networks

BMC Bioinformatics, 2007
Background Metabolic Flux Analysis (MFA) based on isotope labeling experiments (ILEs) is a widely established tool for determining fluxes in metabolic pathways.
Wiechert Wolfgang, Weitzel Michael, Nöh Katharina   +2 more
doaj   +1 more source

Real-time quantitative analysis of volatile products generated during solid-state polypropylene thermal oxidation [PDF]

, 2013
Analysis of volatile organic compounds (VOCs) during PP thermal oxidation under three oxygen partial pressures (0%, 21% and 100% of atmospheric pressure) at 140 C was performed by proton transfer reaction coupled with Fourier transform ion cyclotron ...
COLIN, Xavier, DESNOUX, Eric, FRANCOIS-HEUDE, Alexandre, HENINGER, Michel, LEPROVOST, Julien, MESTDAGH, Helene, RICHAUD, Emmanuel   +6 more
core   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Human neutrophil kinetics: modeling of stable isotope labeling data supports short blood neutrophil half-lives. [PDF]

, 2016
Human neutrophils have traditionally been thought to have a short half-life in blood; estimates vary from 4-18 hours. This dogma was recently challenged by stable isotope labeling studies with heavy water which yielded estimates in excess of 3 days.
Akbulut, Arafa Salam, Asquith, Athens, Becca Asquith, Boggs, Borregaard, Busch, Busch, Cartwright, Chatta, Christoph Niederalt, Colvin, Cronkite, Dancey, Davis, Derek Macallan, Donohue, Ehmann, Elghetany, Fliedner, Friberg, Friberg, Furze, Galbraith, Harrison, Hsieh, Hu, ICRP, ICRP, Jilma, Julio Lahoz-Beneytez, Lambert, Li, Lund-Johansen, Macallan, Macallan, Marjet Elemans, Michael Block, Mishler, Neese, Osgood, Painter, Patt, Pegg, Peters, Pillay, Pillay, Price, Price, Quartino, Rankin, Raya Ahmed, Rocha, Saverymuttu, Soetaert, Suratt, Tak, Terstappen, Vrisekoop, Yan Zhang, Yanokura   +61 more
core   +1 more source

Pyridine-based strategies towards nitrogen isotope exchange and multiple isotope incorporation

Nature Communications
Isotopic labeling is at the core of health and life science applications such as nuclear imaging, metabolomics and plays a central role in drug development. The rapid access to isotopically labeled organic molecules is a sine qua non condition to support
Minghao Feng, Maylis Norlöff, Benoit Guichard, Steven Kealey, Timothée D’Anfray, Pierre Thuéry, Frédéric Taran, Antony Gee, Sophie Feuillastre, Davide Audisio   +9 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source