Results 51 to 60 of about 1,839,261 (340)

Synthesis of isotopically labelled cardiolipins

Tetrahedron Letters, 1998
Abstract A phosphotriester approach is used to access the complex phospholipid, cardiolipin (1) with polyunsaturated fatty acid chains. The synthetic method allows the specific incorporation of isotopic labels within the molecule and sets up the desired configuration at all three chiral centres which corresponds to the configuration of the natural ...
Duralski, A, Spooner, P, Rankin, SE, Watts, A   +3 more
openaire   +2 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Development of High-Performance Chemical Isotope Labeling LC-MS for Profiling the Carbonyl Submetabolome.

Analytical Chemistry, 2017
Metabolites containing a carbonyl group represent several important classes of molecules including various forms of ketones and aldehydes such as steroids and sugars. We report a high-performance chemical isotope labeling (CIL) LC-MS method for profiling
Shuang Zhao, Margot Dawe, Kevin Guo, Liang Li   +3 more
semanticscholar   +1 more source

Nitric oxide‐forming nitrite reductases in the anaerobic ammonium oxidizer Kuenenia stuttgartiensis

FEBS Open Bio, EarlyView.
Anammox bacteria remove fixed nitrogen from their environment via anaerobic ammonium oxidation (anammox) with nitrite as electron acceptor and dinitrogen gas as product. The first anammox step is the conversion of nitrite to nitric oxide by nitrite reductase.
Femke J. Vermeir, Lotte W. Nijman, Robert S. Jansen, Laura van Niftrik, Wouter Versantvoort   +4 more
wiley   +1 more source

Chemical Isotope Labeling LC-MS for High Coverage and Quantitative Profiling of the Hydroxyl Submetabolome in Metabolomics.

Analytical Chemistry, 2016
A key step in metabolomics is to perform accurate relative quantification of the metabolomes in comparative samples with high coverage. Hydroxyl-containing metabolites are an important class of the metabolome with diverse structures and physical/chemical
Shuang Zhao, Xian Luo, Liang Li
semanticscholar   +1 more source

Designing of Self‐Dispersing Soft Dendritic Microcleaners for Microplastics Capture and Recovery

Advanced Functional Materials, EarlyView.
The capture and recovery of microplastics from open aquatic systems is a complex problem, which necessitates nontrivial solutions. The principles of a comprehensive multistage process based on sustainably sourced microcleaners with hierarchical morphology are demonstrated.
Haeleen Hong, Rachel S. Bang, Lucille Verster, Orlin D. Velev   +3 more
wiley   +1 more source

SIMPEL: using stable isotopes to elucidate dynamics of context specific metabolism

Communications Biology
The capacity to leverage high resolution mass spectrometry (HRMS) with transient isotope labeling experiments is an untapped opportunity to derive insights on context-specific metabolism, that is difficult to assess quantitatively.
Shrikaar Kambhampati, Allen H. Hubbard, Somnath Koley, Javier D. Gomez, Frédéric Marsolais, Bradley S. Evans, Jamey D. Young, Doug K. Allen   +7 more
doaj   +1 more source

Using 14C-acetate Pulse-chase Labeling to Study Fatty Acid and Glycerolipid Metabolism in Plant Leaves

Bio-Protocol, 2021
Lipids metabolism is comprised of networks of reactions occurred in different subcellular compartments. Isotopic labeling is a good way to track the transformations and movements of metabolites without perturbing overall cellular metabolism. Fatty acids,
Linhui Yu, Chao Zhou, Jilian Fan, Changcheng Xu   +3 more
doaj   +1 more source

Discovery of an Intrinsic Antiferromagnetic Semiconductor EuSc2Te4 With Magnetism‐Driven Nonlinear Transport

Advanced Functional Materials, EarlyView.
EuSc₂Te₄, an antiferromagnetic semiconductor, exhibits a nonlinear Hall effect (NLHE) characterized by quadratic current–voltage behavior. Combined experimental and theoretical studies reveal that this NLHE is linked to its antiferromagnetism and involves contributions from the quantum metric.
Seng Huat Lee, Yufei Zhao, Noble Gluscevich, Hemian Yi, Zachary Morgan, Huibo Cao, Jahyun Koo, Yu Wang, Jingyang He, Venkatraman Gopalan, Yuanxi Wang, Weiwei Xie, CuiZu Chang, Qiang Zhang, Binghai Yan, Zhiqiang Mao   +15 more
wiley   +1 more source

Molecular elucidating of an unusual growth mechanism for polycyclic aromatic hydrocarbons in confined space

Nature Communications, 2020
Coke-induced catalyst deactivation draws increasing concerns in industrially catalytic processes. Here the authors provide a strategy integrating advanced mass spectroscopy and isotope labeling to uncover a cage-passing molecular route of coking species ...
Nan Wang, Yuchun Zhi, Yingxu Wei, Wenna Zhang, Zhiqiang Liu, Jindou Huang, Tantan Sun, Shutao Xu, Shanfan Lin, Yanli He, Anmin Zheng, Zhongmin Liu   +11 more
doaj   +1 more source