Results 171 to 180 of about 78,627 (266)

Palladium-Catalyzed Synthesis of 5‑Formyl-2'-Deoxycytidine, 5‑Carboxyl-2'-Deoxycytidine, and Nitrogen-15-Labeled Derivatives via Ex Situ-Generated Carbon Monoxide from Chloroform and Application in Isotope Dilution LC-MS/MS Analysis of DNA. [PDF]

ACS Omega
Stefoudi E, Terzidis MA.
europepmc   +1 more source

Structural and Functional Siderophore Remodeling by Enzymatic Delipidation

Angewandte Chemie, EarlyView.
A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog, Keishi Ishida, Evelyn M. Molloy, Ron Hermenau, Kirstin Scherlach, Christian Hertweck   +5 more
wiley   +1 more source

Correction to "Stable Isotope Reference Materials and Scale Definitions-Outcomes of the 2024 IAEA Experts Meeting". [PDF]

Rapid Commun Mass Spectrom
europepmc   +1 more source

Stable isotope labelling mass spectrometry analysis of isolated mouse sperm. [PDF]

Biol Reprod
Dobson G, Balbach M.
europepmc   +1 more source

Key Drivers of Activity and Selectivity in Cu‐Based Catalysts for Methanol Synthesis From CO2: Insights From Atomically Dispersed Promoters

Angewandte Chemie, EarlyView.
Mechanistic studies on model Cu─M/SiO2 catalysts (M = Zn, Ga, and In) reveal that promoters enable a formate spillover pathway from Cu to Mn+ (n = 2 or 3) sites. The promoter's electronic effect on formate bond strengths serves as a quantitative descriptor for activity and selectivity, balancing spillover dynamics with intermediate stabilization to ...
Nat Phongprueksathat, Gina Noh, Scott R. Docherty, Damian Vico van Berkel, Yannik Stiefel, Christophe Copéret, Atsushi Urakawa   +6 more
wiley   +1 more source

Modulating Local Coordination in Single‐Atom Catalysts: From Fundamental Concepts to Emerging Breakthroughs in Electrocatalysis

Angewandte Chemie, EarlyView.
This review summarizes atomic‐level design strategies for single‐atom catalysts, emphasizing modulation of the local coordination environment, active‐site geometry, and metal‐support interactions to optimize catalytic activity and stability in electrocatalytic energy conversion applications.
Ashwani Kumar, Harun Tüysüz
wiley   +1 more source

Mass spectrometry proteomics for studying mitostasis. [PDF]

Protein Sci
Sharma L, Chakroborty S, Das H, Oeljeklaus S, Bender J, Warscheid B.   +5 more
europepmc   +1 more source

Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization

Angewandte Chemie, EarlyView.
The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu, Zeliang Zhang, Benedikt Seligmann, Van Hung Bui, Tuan‐Anh Minh Nguyen, Thu‐Thuy T. Dang, Jakob Franke   +6 more
wiley   +1 more source

Intramolecularly Labeled Reference Standards of Sulfamethoxazole for Fragment-Specific Isotope Analysis by Electrospray Ionization Orbitrap Mass Spectrometry. [PDF]

J Am Soc Mass Spectrom
Canavan A, Dirr C, Elsner M.
europepmc   +1 more source

Rhenium‐Based β‐Galactosidase Probe Allows Senescence Profiling by Mass Cytometry

Angewandte Chemie, EarlyView.
Senescence‐associated β‐galactosidase (SA‐β‐Gal) activity is a widely accepted biomarker of cellular senescence, yet its integration with other senescence markers has been limited by available detection methods. Here, we introduce ReGal, a mass cytometry‐compatible SA‐β‐Gal activity probe that can be multiplexed with established markers of senescence ...
Adam Tam, Kris Elbein, Aleida G. Gonzalez, Edgar A. Arriaga, Mark Nitz   +4 more
wiley   +1 more source