Results 221 to 230 of about 78,627 (266)
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Isotope dilution mass spectrometry
International Journal of Mass Spectrometry and Ion Processes, 1992Abstract In the past isotope dilution mass spectrometry (IDMS) has usually been applied using the formation of positive thermal ions of metals. Especially in calibrating other analytical methods and for the certification of standard reference materials this type of IDMS became a routine method.
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Elemental and Isotopic Mass Spectrometry
2015Abstract Analytical challenges of elemental and isotope food analysis are discussed, introducing the fundamental principles of different techniques such as ICP-MS, IRMS, TIMS, and their variants such as MC-ICP-MS, LC-ICP-MS, FFF-ICP-MS, and GC-IRMS. Applications are discussed and commented.
Constantinos A. Georgiou +1 more
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Isotope dilution mass spectrometry of cholesterol in serum
Biological Mass Spectrometry, 1981Isotope dilution mass spectrometry is one of the best candidates for reference and definitive methods for the quantitative measurement of organic compounds. In this study sources of error were investigated. Where possible they were removed, and commercially available equipment had to be modified.
Freudenthal, J +4 more
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Detection Limit of Isotope Dilution Mass Spectrometry
Analytical Chemistry, 2002The detection limit is an important figure of merit for evaluating instrumentation and analytical methods. While the detection limit for techniques using linear calibration functions has been studied extensively, this fundamental metric has rarely been discussed for mass spectrometry that bases the calibration on the principle of isotope dilution.
Lee L, Yu +2 more
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Stable isotope-coded proteomic mass spectrometry
Current Opinion in Biotechnology, 2003Developing the ability to quantify changes in protein abundance between cells subjected to a variety of physiological and environmental conditions is an extremely active area of proteome research. Although advances in chromatography, mass spectrometry instrumentation, and bioinformatics have contributed to producing a viable method for comparative ...
Michael B, Goshe, Richard D, Smith
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Isotope-Dilution Mass Spectrometry in Clinical Chemistry
1985Publisher Summary This chapter discusses isotope dilution mass spectrometry in clinical chemistry. Mass spectrometry (MS) in clinical chemistry is increasingly used as an analytical tool to solve complex problems in biochemistry and medicine. As a matter of fact, there are five ways that mass spectrometry can be applied to problems in these areas: (1)
A P, De Leenheer +3 more
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The Determination of Isotopic Masses and Abundances by Mass Spectrometry
Zeitschrift für Elektrochemie, Berichte der Bunsengesellschaft für physikalische Chemie, 1954AbstractA brief re view of mass spectrometry is given with special emphasis on the use of double focusing mass spectrometers. Recent work on the determination of precise atomic masses is discussed. A Table showing the comparison between the 1953 International Table of Atomic Weights and atomic weights calculated from physical measurements alone is ...
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Mass Spectrometry and Stable Isotopes
1990Investigation of inherited metabolic disorders requires methods which have the ability to apply to a vast array of metabolites of different chemical classes, unambiguously identify known as well as previously unknown metabolites, precisely quantify the substrates in question in a variety of body fluids, and quantitfy the movement (kinetics) of these ...
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Mass Spectrometry and Isotope Geochemistry
2017Much of the most promising modern Earth Science depends on the measurements and observations that can no longer be obtained with a hammer, Brunton compass, and hand lens alone. Although much that is important is still being done and will continue to be done in this way by first class minds, new expensive and frequently unavailable instrumentation is ...
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Isotope mass spectrometry in metrology
Mass Spectrometry Reviews, 1992John R. De Laeter +2 more
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