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Isotopic Distribution Calibration for Mass Spectrometry

Analytical Chemistry, 2021
Mass spectrometry (MS) is widely used in science and industry. It allows accurate, specific, sensitive, and reproducible detection and quantification of a huge range of analytes. Across MS applications, quantification by MS has grown most dramatically, with >50 million experiments/year in the USA alone.
Anthony D. Maus   +4 more
openaire   +2 more sources

Isotope ratio mass spectrometry

The Analyst, 2009
Isotope Ratio Mass Spectrometry (IRMS) is a specialized technique used to provide information about the geographic, chemical, and biological origins of substances. The ability to determine the source of an organic substance stems from the relative isotopic abundances of the elements which comprise the material.
Zeland, Muccio, Glen P, Jackson
openaire   +2 more sources

Isotope correction of mass spectrometry profiles

Rapid Communications in Mass Spectrometry, 2008
Abstract Isotope correction of a profile is an important step in the analysis of mass spectrometry derived data. The problem is mathematically formulated as a system of linear equations which is general enough to include previous correction methods.
Günther, Eibl   +5 more
openaire   +2 more sources

Isotope Dilution Mass Spectrometry

2013
Isotope Dilution Mass Spectrometry (IDMS) has become an essential tool in research laboratories and is increasingly used in routine analysis labs (including environmental, food safety and clinical applications). This is the first textbook to present a comprehensive and instructive view of the theory and applications of this growing technique.
Jose Alonso, Pablo Gonzalez
openaire   +1 more source

Mass spectrometry and isotopes: A century of research and discussion

Mass Spectrometry Reviews, 2005
AbstractIn 1815, the British physician William Prout had advanced the theory that the molecular masses of elements were multiples of the mass of hydrogen. This “whole number rule” (and especially deviations from it) played an important role in the discussion whether elements could be mixtures of isotopes. F.
Herbert, Budzikiewicz, Ronald D, Grigsby
openaire   +2 more sources

Isotope dilution mass spectrometry

International Journal of Mass Spectrometry and Ion Processes, 1992
Abstract In the past isotope dilution mass spectrometry (IDMS) has usually been applied using the formation of positive thermal ions of metals. Especially in calibrating other analytical methods and for the certification of standard reference materials this type of IDMS became a routine method.
openaire   +1 more source

Elemental and Isotopic Mass Spectrometry

2015
Abstract Analytical challenges of elemental and isotope food analysis are discussed, introducing the fundamental principles of different techniques such as ICP-MS, IRMS, TIMS, and their variants such as MC-ICP-MS, LC-ICP-MS, FFF-ICP-MS, and GC-IRMS. Applications are discussed and commented.
Constantinos A. Georgiou   +1 more
openaire   +1 more source

Detection Limit of Isotope Dilution Mass Spectrometry

Analytical Chemistry, 2002
The detection limit is an important figure of merit for evaluating instrumentation and analytical methods. While the detection limit for techniques using linear calibration functions has been studied extensively, this fundamental metric has rarely been discussed for mass spectrometry that bases the calibration on the principle of isotope dilution.
Lee L, Yu   +2 more
openaire   +2 more sources

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