Results 111 to 120 of about 67,280 (303)
Double isotope dilution derivative assay of digitoxin in plasma, urine, and stool of patients maintained on the drug. [PDF]
Davorka Lukas, Ralph E. Peterson
openalex +1 more source
The complex centered on Ghd7 binds to numerous carbon and nitrogen metabolism genes on the genome through the corresponding motifs and transactivates the transcriptional expression of these carbon and nitrogen metabolism genes. With the assistance of OsNAC42 and other unknown Ghd7‐interacting proteins, this complex can regulate different metabolic ...
Guangming Lou+23 more
wiley +1 more source
Impact des modes de gestion de la fertilité du sol et des systèmes de cultures sur la nutrition azotée et les rendements du mil (Pennisetum glaucum (L.) R. Br.) au Niger [PDF]
Impact of Soil Fertility Management Practices and Cropping systems on Nitrogen Nutrition and Yields of Millet (Pennisetum glaucum (L.) R.Br.) in Niger. To identify the best methods of soil fertility management in Sahel conditions, the following objects ...
Hamidou, Z.+5 more
doaj
Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu+9 more
wiley +1 more source
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng+40 more
wiley +1 more source
Evidence for O-atom exchange in the O(^1D) + N_2O reaction as the source of mass-independent isotopic fractionation in atmospheric N_2O [PDF]
Recent experiments have shown that in the oxygen isotopic exchange reaction for O(^1D) + CO_2 the elastic channel is approximately 50% that of the inelastic channel [Perri et al., 2003].
Blake, Geoffrey A.+4 more
core
Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez+20 more
wiley +1 more source
Structural modification of clofoctol yielded a novel blood‐brain barrier‐permeable compound, B7, featuring a multi‐substituted diaryl scaffold. B7 demonstrates potent anti‐glioblastoma activity by suppressing glioblastoma stem cells proliferation, migration, and invasion through interactions with five key residues of poliovirus receptor cell adhesion ...
Yong‐jian Wang+9 more
wiley +1 more source
CO Line Emission and Absorption from the HL Tau Disk: Where is all the dust?
We present high-resolution infrared spectra of HL Tau, a heavily embedded young star. The spectra exhibit broad emission lines of hot CO gas as well as narrow absorption lines of cold CO gas. The column density for this cooler material (7.5+/-0.2 x 10^18
Carr J. S.+7 more
core +1 more source
A bioluminescent probe, BLGLN, comprising BL568 and ASCT2‐uptaken AA201, enables real‐time monitoring and evaluation of ASCT2‐mediated glutamine uptake rates in living tumors via Staudinger ligation, aiding tumor metabolism studies and targeted therapeutics.
Bing‐Jun Zhou+9 more
wiley +1 more source