Results 61 to 70 of about 54,813 (313)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Unveiling the metabolic fate of monosaccharides in cell membranes with glycomic and glycoproteomic analyses. [PDF]

, 2019
Cell membrane protein glycosylation is dependent on the metabolic state of the cell as well as exogenous nutrients available. Although the metabolism and interconversion of monosaccharides have been well-studied, their incorporation into cell surface ...
Cheng, Zhi, Lebrilla, Carlito B, Li, Qiongyu, Park, Dayoung, Wong, Maurice, Xu, Gege   +5 more
core  

Finiteness of classifying spaces of relative diffeomorphism groups of 3-manifolds

, 1997
The main theorem shows that if M is an irreducible compact connected orientable 3-manifold with non-empty boundary, then the classifying space BDiff(M rel dM) of the space of diffeomorphisms of M which restrict to the identity map on boundary(M) has the ...
Allen Hatcher, Darryl McCullough, Gramain, Hatcher, Hatcher, Hatcher, Heil, Ivanov, Jaco, Johannson, Kalliongis, Laudenbach, McCullough, Serre, Tollefson, Waldhausen, Waldhausen   +16 more
core   +3 more sources

Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women [PDF]

, 1999
Background: We studied the oxidation of an oil rich in docosahexaenoic acid (DHA; DHASCO(R)) in lactating mothers receiving a dietary DHA supplement or a placebo. The results were compared with the oxidation of linoleic acid.
Demmelmair, Hans, Fidler, N., Koletzko, Berthold, Pohl, A., Sauerwald, T.   +4 more
core   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Absorption and distribution of different forms of nitrogen in two legumes and organs

Guangxi Zhiwu, 2023
Legumes are abundant in the nitrogen deficient desert ecosystems, which is the center of supplying available nitrogen and the important pioneer species in this region.
Erfan AKBERJAN, Jin LI, Weiwei ZHUANG
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

MATRIX platform to analyze translation machinery remodeling in glioblastoma cells

STAR Protocols, 2022
Summary: Here, we present a protocol using MATRIX (mass spectrometry analysis of active translation factors using ribosome density fractionation and isotopic labeling experiments) platform to investigate changes of the protein synthesis machinery in ...
J.J. David Ho, Tyler A. Cunningham, Jonathan R. Krieger, Jonathan H. Schatz, Stephen Lee   +4 more
doaj   +1 more source

Isotope Labeling in Mammalian Cells [PDF]

, 2011
Isotope labeling of proteins represents an important and often required tool for the application of nuclear magnetic resonance (NMR) spectroscopy to investigate the structure and dynamics of proteins. Mammalian expression systems have conventionally been considered to be too weak and inefficient for protein expression.
Arpana, Dutta, Krishna, Saxena, Harald, Schwalbe, Judith, Klein-Seetharaman   +3 more
openaire   +2 more sources

Atomic Size Misfit for Electrocatalytic Small Molecule Activation

Advanced Functional Materials, EarlyView.
This review explores the application and mechanisms of atomic size misfit in catalysis for small molecule activation, focusing on how structural defects and electronic properties can effectively lower the energy barriers of chemical bonds in molecules like H2O, CO2, and N2.
Ping Hong, Changfan Xu, Huaping Zhao, Yong Lei   +3 more
wiley   +1 more source