Results 141 to 150 of about 15,919 (176)
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Isotretinoin: A Reappraisal

Drug Intelligence & Clinical Pharmacy, 1984
Isotretinoin is remarkably effective in the treatment of severe cystic acne, however, many complications have been observed during treatment and new toxic effects have been reported. Hypertriglyceridemia associated with decreases in high density lipoprotein (HDL) cholesterol has occurred in 25 percent of patients and requires monitoring during ...
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Isotretinoin‐Induced Agranulocytosis

Pediatric Dermatology, 2007
Abstract:  Isotretinoin is used to treat a spectrum of dermatologic conditions. The present article reports the case of a 15‐year‐old female patient who exhibited agranulocytosis after the initiation of isotretinoin administration. Agranulocytosis is a rare but life‐threatening side effect of isotretinoin use, and clinicians must be aware of ...
Patiroglu, Türkan   +5 more
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Perspective on Isotretinoin

Archives of Dermatology, 1984
To the Editor.— The frequent use of isotretinoin (Accutane) reminds me of the adage when penicillin was first introduced: "If an injection of penicillin doesn't cure the condition it's advisable to examine the patient." The following anecdotal reports are limited and uncontrolled, but I wonder what a controlled objective report of isotretinoin ...
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Treatment of Rosacea with Isotretinoin

International Journal of Dermatology, 1986
ABSTRACT: A multicenter trial of isotretinoin in severe papulopustular rosacea in adult patients was undertaken to evaluate the efficacy and safety of this treatment. A 20‐week course of therapy was instituted in 92 patients from 11 dermatology departments.
Gerd Plewig, E. Hoting, E. Paul
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Isotretinoin: Which dosage? [PDF]

open access: possibleAustralasian Journal of Dermatology, 1997
SUMMARYLong‐term clinical experience with isotretinoin has confirmed both therapeutic effectiveness and the ability to induce prolonged remission. Numerous authors have demonstrated the importance of cumulative dose in achieving stable remission.
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Isotretinoin-associated proctosigmoiditis

Gastroenterology, 1987
A 17-yr-old boy developed acute proctosigmoiditis after the institution of isotretinoin for the treatment of cystic acne vulgaris. Painless diarrhea, accompanied by mucus and eventually blood, began within days of commencing treatment and persisted while the drug was administered.
P. Martin   +3 more
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Response of rosacea to isotretinoin

Clinical and Experimental Dermatology, 1984
Summary We have treated seven patients with severe rosacea with 1 mg kg−1 day−1 isotretinoin for 12 weeks. There were large reductions in numbers of papules and pustules (P < 0.001) small decreases in measurements of erythema (P < 0.01) and median values for severity were lower during and after treatment.
Sam Shuster, M. Neugebauer, J.R. Marsden
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Updates in Isotretinoin

2021
Isotretinoin therapy has been studied a great deal over the past decade, with new understanding about its use in the treatment of acne vulgaris. Optimal dosing for isotretinoin therapy has yet to be elucidated, although data supports that lower relapse rates are seen with higher cumulative doses of medication.
Katherine A. Berry   +2 more
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Sacroiliitis secondary to isotretinoin

Australasian Journal of Dermatology, 2011
ABSTRACTReported is the case of a 17‐year old male with sacroiliitis confirmed by magnetic resonance imaging (MRI) while undergoing isotretinoin treatment for acne vulgaris. The cessation of isotretinoin and symptomatic treatment resolved the symptoms within 6 weeks, with no signs of sacroiliitis on repeat MRI 10 months later.
Andrew Gibson   +2 more
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The Isotretinoin Teratogen Syndrome

Obstetrical & Gynecological Survey, 1984
Two infants with prominent frontal bossing, hydrocephalus, microphthalmia, and small, malformed, low-set, undifferentiated ears were born to mothers who had taken isotretinoin in the first trimester of pregnancy. A Dandy-Walker malformation, microcephaly, hypertelorism, small ear canals, cleft palate, small mouth, and congenital heart disease were also
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