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Isoxazolin-5-one

Journal of the Chemical Society C: Organic, 1971
The reaction paths leading from ethyl propiolate to isoxazolin-5-one (II) and isoxazolin-3-one (III) are discussed and shown to be pH-dependent. The chemical and tautomeric properties of compound (II) are consistent with the known behaviour of its derivatives.
DE SARLO, FRANCESCO   +2 more
openaire   +2 more sources

Design and synthesis of sarolaner, a novel, once-a-month, oral isoxazoline for the control of fleas and ticks on dogs

open access: yesBioorganic and Medicinal Chemistry Letters, 2016
Over the last decade, the isoxazoline motif has become the intense focus of crop protection and animal health companies in their search for novel pesticides and ectoparasiticides.
Debra J Woods, Aleah Pullins
exaly   +2 more sources

Isoxazoline

2005
The first part of the presented work deals with the enantioselective synthesis of isoxazolines. The synthetic approach involves the asymmetrically catalysed 1,3-dipolar cycloaddition of nitrones to acetylenes. Therefore electrondeficient mono- and bifunctionalysed as well as electronrich triplebond systems, in combination with electronrich and ...
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