Results 21 to 30 of about 84,898 (278)

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

open access: yesAngewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

The role of glutamine synthetase isozymes in enhancing nitrogen use efficiency of N-efficient winter wheat

open access: yesScientific Reports, 2017
Glutamine synthetase (GS) isozymes play critical roles in nitrogen (N) metabolism. However, the exact relationship between GS and nitrogen use efficiency (NUE) remain unclear.
Zhiyong Zhang   +5 more
doaj   +1 more source

Structural and biophysical analysis of important biomedical enzymes and nano-architectures [PDF]

open access: yes, 2008
Dopa decarboxylase (DDC) is an important enzyme in the catecholamine biosynthesis pathways. Catecholamines, e.g., dopamine, serotonin, etc. often are the major neuromodulators or neurotransmitters.
Chattopadhyay, Arundhati
core   +1 more source

Isozyme variation in four species of the Simulium perflavum species group (Diptera: Simuliidae) from the Brazilian Amazon

open access: yesGenetics and Molecular Biology, 2003
Electrophoretic studies of isozymes were done with four closely related species of the Simulium perflavum species group (Diptera: Simuliidade) in the Brazilian Amazon, using last-instar larvae collected in the field.
Vera Margarete Scarpassa, Neusa Hamada
doaj   +1 more source

A role for glyceraldehyde-3-phosphate dehydrogenase in the development of thermotolerance in Xenopus laevis embryos [PDF]

open access: yes, 1988
During heat shock, Xenopus laevis embryos exhibit an increase in the rate of accumulation of lactate and a loss of ATP relative to non-heat- shocked control embryos.
Browder, Leon W., Nickells, Robert W.
core   +2 more sources

Diversity and genetic struture in cajá tree (spondias mombin l.) populations in northeastern Brazil Diversidade e estrutura genética de populações em cajazeira (spondias mombin l.) no nordeste do Brasil

open access: yesRevista Brasileira de Fruticultura, 2009
Spondias mombin L. is a fruit tree from the American continent from the Anacardiaceae family. In Brazil it is common in different vegetation types but is more frequent in the Atlantic and Amazonian rainforests. It is economically important because of its
Edson Ferreira da Silva   +2 more
doaj   +1 more source

Genetic similarity of citrus fresh fruit market cultivars Similaridade genética de cultivares de citros de mesa

open access: yesRevista Brasileira de Fruticultura, 2005
The objective of this work was to assess the genetic similarity of the following citrus fresh fruit market seedless cultivars: Lane Late, Navelate, Navelina and Salustiana sweet oranges (Citrus sinensis (L.) Osbeck), Clemenules and Marisol mandarins (C ...
Roberto Pedroso de Oliveira   +1 more
doaj   +1 more source

Effect of aluminium on peroxidase activity in roots of Al-sensitive and Al-resistant barley cultivars

open access: yesPlant, Soil and Environment, 2002
The effect of Al stress on peroxidase activity and peroxidase isozymes was studied in roots of two barley cultivars with contrasting sensitivity to Al. Al treatment induced a tremendous enhancement of guaiacol peroxidase activity especially in roots of ...
L. Tamás, J. Huttová, I. Mistrík
doaj   +1 more source

Heterologous expression and biochemical characterisation of fourteen esterases from Helicoverpa armigera. [PDF]

open access: yesPLoS ONE, 2013
Esterases have recurrently been implicated in insecticide resistance in Helicoverpa armigera but little is known about the underlying molecular mechanisms. We used a baculovirus system to express 14 of 30 full-length esterase genes so far identified from
Mark G Teese   +8 more
doaj   +1 more source

A new continuous cell line from the mosquito Psorophora confinnis (Diptera: Culicidae) and its susceptibility to infections with some arboviruses

open access: yesMemorias do Instituto Oswaldo Cruz, 2001
A new cell line, PC-0199-BR, was established from embryonated eggs of the mosquito Psorophora confinnis. To date (September 2000) it has had 62 continuous passages.
Felio J Bello   +6 more
doaj   +1 more source

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