Results 41 to 50 of about 40,983 (226)
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo +5 more
wiley +1 more source
Rhodanese isozymes in human tissues
, 1988 An investigation of a range of tissue homogenates by various electrophoretic methods, followed by staining for specific enzyme activity, has revealed a series of isozymes of human rhodanese.
WHITEHOUSE D. B. +3 more
core +1 more source
The FEBS Journal, EarlyView.The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati +4 more
wiley +1 more source
Plants, 2021 In this study, the anti-stress capabilities of the foliar application of chitosan, dissolved in four different organic acids (acetic acid, ascorbic acid, citric acid and malic acid) have been investigated on tomato (Solanum lycopersicum L.) plants under ...
Mohamed S. Attia +6 more
doaj +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Sesame (Sesamum indicum L., 2n = 26) is one of the oldest oilseed crops and is often called the ‘queen of oilseeds’ due to its high content of unsaturated fatty acids and natural antioxidants. Despite its long history, the origin and global spread of cultivated sesame remain unresolved.
Weifei Yang +16 more
wiley +1 more source
Identification of ADP-ribosylation site in human glutamate dehydrogenase isozymes [PDF]
, 2005 When the influence of ADP-ribosylation on the activities of the purified human glutamate dehydrogenase isozymes (hGDH1 and hGDH2) was measured in the presence of 100μM NAD+ for 60min, hGDH isozymes were inhibited by up to 75%.
Seung-Ju Yang +11 more
core +1 more source
Análise genética de fenótipos isoenzimáticos e desequilíbrio de ligação em Myracrodruon urundeuva Fr. All. Genetic analysis of isoenzymes phenotypes and linkage disequilibrium in Myracrodruon urundeuva Fr. All. [PDF]
Revista do Instituto Florestal, 2004 A herança e o desequilíbrio de ligaçãoforam estudadas em seis locos polimórficos (Got-1,Got-2, Lap-1, 6pgdh-1, Pgi-2 e Pgm-1) de cincosistemas isoenzimáticos (GOT, LAP, PGI, 6PGD ePGM) revelados em 55 progênies de polinizaçãoaberta de duas populações de ...
Alexandre Magno SEBBENN +3 more
doaj
Czech Journal of Genetics and Plant Breeding, 2009 Environmental (geographic location, year-to-year effect) and genetic (intravarietal variation) effects on the stability of the isozyme patterns of esterase (EST), acid phosphatase (ACP), alcohol dehydrogenase (ADH), leucine aminopeptidase (LAP ...
Jiří HORÁČEK +3 more
doaj +1 more source
Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta
Plant, Cell &Environment, EarlyView.ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng +7 more
wiley +1 more source
Czech Journal of Genetics and Plant Breeding, 2015 Genetic variation within and among fifteen Trifolium species represented by 157 accessions was assessed using morphological and isozyme markers. Most of morphometric characters contributed to the discrimination of the species. No significant relationship
Imane MEDOUKALI +2 more
doaj +1 more source